| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 34 | 34 | 11 | 12 | 5.00 | .338 | 1.48 | 9.2 | 4.1 | 6.7 | 223.0 | 229 | 129 | 124 | 31 | 101 | 165 | 4 | 0 | 0 | 0 | 16 | 12 | 3 | 4.85 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 80 | 34 | 33 | 12 | 9 | 4.63 | .321 | 1.39 | 9.4 | 3.2 | 6.4 | 194.1 | 202 | 110 | 100 | 33 | 68 | 139 | 3 | 0 | 0 | 1 | 17 | 6 | 2 | 4.92 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 32 | 32 | 10 | 11 | 5.19 | .331 | 1.43 | 10.5 | 2.4 | 6.5 | 185.2 | 216 | 110 | 107 | 27 | 50 | 134 | 4 | 0 | 0 | 1 | 13 | 9 | 0 | 4.41 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 32 | 32 | 8 | 5 | 5.56 | .341 | 1.51 | 10.0 | 3.6 | 5.4 | 126.1 | 140 | 79 | 78 | 14 | 51 | 76 | 0 | 0 | 0 | 0 | 3 | 5 | 2 | 4.57 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 34 | 31 | 8 | 12 | 5.82 | .341 | 1.53 | 10.3 | 3.5 | 6.7 | 179.1 | 205 | 118 | 116 | 44 | 69 | 133 | 1 | 0 | 1 | 0 | 12 | 5 | 0 | 5.95 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 86 | 107 | 0 | 12 | 3 | 3.54 | .302 | 1.23 | 7.2 | 4.0 | 8.9 | 129.2 | 103 | 54 | 51 | 14 | 57 | 127 | 0 | 2 | 4 | 0 | 0 | 8 | 9 | 3.95 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 103 | 0 | 7 | 4 | 4.02 | .306 | 1.29 | 8.3 | 3.3 | 8.8 | 134.1 | 124 | 61 | 60 | 15 | 49 | 131 | 0 | 6 | 4 | 0 | 0 | 5 | 0 | 3.71 |
| SU | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 92 | 0 | 6 | 6 | 5.08 | .345 | 1.56 | 8.8 | 5.2 | 8.4 | 117.0 | 115 | 68 | 66 | 16 | 68 | 109 | 0 | 4 | 9 | 0 | 0 | 2 | 3 | 4.71 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 34 | 104 | 0 | 3 | 1 | 3.24 | .338 | 1.47 | 9.3 | 4.1 | 9.3 | 33.1 | 34 | 12 | 12 | 7 | 15 | 34 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 5.24 |