| SP | Morton, C.Morton, Charlie >> | 38 | 2021 | R | 94 | 9 | 9 | 2 | 5 | 4.24 | .301 | 1.24 | 9.3 | 1.9 | 10.6 | 57.1 | 59 | 28 | 27 | 8 | 12 | 67 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 3.26 |
| SP | Berrios, J.Berrios, Jose >> | 27 | 2021 | R | 84 | 8 | 8 | 2 | 5 | 7.26 | .360 | 1.64 | 10.8 | 4.2 | 7.8 | 39.2 | 47 | 32 | 32 | 5 | 18 | 34 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.46 |
| SP | Sandoval, P.Sandoval, Patrick # >> | 24 | 2021 | L | 72 | 8 | 8 | 3 | 3 | 4.95 | .328 | 1.42 | 9.6 | 3.3 | 10.3 | 43.2 | 46 | 25 | 24 | 8 | 16 | 49 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 4.40 |
| SP | Civale, A.Civale, Aaron >> | 26 | 2021 | R | 68 | 8 | 8 | 3 | 2 | 5.61 | .366 | 1.73 | 12.6 | 3.1 | 7.3 | 43.1 | 60 | 31 | 27 | 8 | 15 | 35 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.84 |
| SP | Taillon, J.Taillon, Jameson >> | 29 | 2021 | R | 57 | 8 | 8 | 2 | 2 | 5.09 | .348 | 1.52 | 9.9 | 4.1 | 7.4 | 40.2 | 44 | 25 | 23 | 9 | 18 | 33 | 0 | 0 | 0 | 0 | 1 | 3 | 0 | 5.85 |
| RP | Karinchak, J.Karinchak, James >> | 25 | 2021 | R | 76 | 23 | 0 | 0 | 2 | 4.44 | .397 | 1.94 | 9.0 | 8.7 | 8.7 | 26.1 | 26 | 13 | 13 | 2 | 25 | 25 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 5.08 |
| RP | Stammen, C.Stammen, Craig >> | 37 | 2021 | R | 63 | 20 | 0 | 1 | 0 | 2.93 | .233 | 0.91 | 7.2 | 1.2 | 7.5 | 30.2 | 24 | 10 | 10 | 6 | 4 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |
| RP | Kinley, T.Kinley, Tyler >> | 30 | 2021 | R | 53 | 17 | 0 | 0 | 1 | 5.30 | .356 | 1.55 | 12.0 | 2.5 | 7.5 | 18.2 | 24 | 11 | 11 | 3 | 5 | 15 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 4.67 |
| SP | Pivetta, N.Pivetta, Nick >> | 28 | 2021 | R | 44 | 1 | 0 | 0 | 0 | 0.00 | .500 | 3.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |