| SP | Buehler, W.Buehler, Walker # >> | 26 | 2021 | R | 95 | 6 | 6 | 1 | 2 | 4.38 | .288 | 1.11 | 8.3 | 1.7 | 8.8 | 37.0 | 34 | 22 | 18 | 9 | 7 | 36 | 0 | 0 | 0 | 0 | 3 | 4 | 1 | 5.11 |
| SP | Alcantara, S.Alcantara, Sandy >> | 25 | 2021 | R | 78 | 6 | 6 | 1 | 1 | 4.12 | .293 | 1.22 | 8.8 | 2.3 | 6.9 | 39.1 | 38 | 18 | 18 | 3 | 10 | 30 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 3.31 |
| SP | Gonzales, M.Gonzales, Marco >> | 29 | 2021 | L | 63 | 5 | 5 | 0 | 3 | 6.31 | .374 | 1.75 | 10.8 | 5.4 | 5.8 | 25.2 | 30 | 18 | 18 | 3 | 15 | 16 | 0 | 0 | 0 | 0 | 2 | 1 | 2 | 5.20 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 96 | 17 | 0 | 2 | 1 | 3.43 | .284 | 1.10 | 7.7 | 2.1 | 8.1 | 21.0 | 18 | 10 | 8 | 1 | 5 | 19 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2.81 |
| RP | Bleier, R.Bleier, Richard >> | 34 | 2021 | L | 68 | 15 | 0 | 1 | 3 | 4.64 | .304 | 1.27 | 9.0 | 2.6 | 6.9 | 21.1 | 21 | 12 | 11 | 2 | 6 | 16 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.71 |
| RP | Alvarez, J.Alvarez, Jose >> | 32 | 2021 | L | 59 | 14 | 0 | 1 | 1 | 1.47 | .214 | 0.82 | 5.0 | 2.5 | 5.5 | 18.1 | 10 | 5 | 3 | 2 | 5 | 11 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.06 |
| SP | Greinke, Z.Greinke, Zack >> | 38 | 2021 | R | 52 | 6 | 0 | 1 | 2 | 2.65 | .329 | 1.41 | 9.0 | 3.7 | 9.0 | 17.0 | 17 | 5 | 5 | 1 | 7 | 17 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.18 |