| SP | Rodon, C.Rodon, Carlos >> | 28 | 2021 | L | 98 | 6 | 6 | 2 | 2 | 2.27 | .246 | 0.98 | 6.7 | 2.3 | 9.5 | 35.2 | 26 | 9 | 9 | 2 | 9 | 37 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 2.40 |
| SP | Ohtani, S.Ohtani, Shohei >> | 26 | 2021 | R | 90 | 5 | 5 | 2 | 1 | 4.06 | .256 | 1.03 | 7.0 | 2.3 | 11.3 | 31.0 | 24 | 15 | 14 | 8 | 8 | 39 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.61 |
| SP | Giolito, L.Giolito, Lucas >> | 26 | 2021 | R | 83 | 5 | 5 | 2 | 2 | 2.93 | .287 | 1.21 | 6.6 | 4.5 | 13.2 | 30.2 | 22 | 11 | 10 | 3 | 15 | 44 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 2.87 |
| SP | Gallen, Z.Gallen, Zac $ >> | 25 | 2021 | R | 45 | 5 | 5 | 2 | 0 | 2.48 | .310 | 1.28 | 6.2 | 5.3 | 8.4 | 29.0 | 20 | 9 | 8 | 4 | 17 | 27 | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 4.90 |
| SU | Jansen, K.Jansen, Kenley >> | 33 | 2021 | R | 93 | 11 | 0 | 0 | 1 | 7.36 | .365 | 1.64 | 9.8 | 4.9 | 7.4 | 11.0 | 12 | 11 | 9 | 2 | 6 | 9 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.64 |
| RP | Loaisiga, J.Loaisiga, Jonathan >> | 26 | 2021 | R | 73 | 14 | 0 | 1 | 0 | 2.25 | .238 | 0.94 | 7.9 | 0.6 | 6.8 | 16.0 | 14 | 5 | 4 | 2 | 1 | 12 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Romano, J.Romano, Jordan >> | 28 | 2021 | R | 88 | 7 | 0 | 1 | 0 | 1.23 | .313 | 1.23 | 7.7 | 3.9 | 7.7 | 7.1 | 6 | 1 | 1 | 0 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.00 |