| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 26 | 26 | 8 | 9 | 3.99 | .316 | 1.35 | 7.7 | 4.5 | 8.3 | 169.0 | 144 | 79 | 75 | 21 | 84 | 156 | 1 | 0 | 0 | 1 | 15 | 6 | 4 | 4.37 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 24 | 24 | 8 | 12 | 4.03 | .313 | 1.33 | 8.7 | 3.2 | 8.8 | 172.0 | 167 | 95 | 77 | 23 | 62 | 168 | 3 | 0 | 0 | 0 | 16 | 6 | 1 | 3.97 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 25 | 25 | 10 | 11 | 5.19 | .321 | 1.39 | 8.4 | 4.0 | 4.9 | 163.0 | 153 | 98 | 94 | 20 | 73 | 89 | 9 | 0 | 0 | 3 | 7 | 5 | 3 | 4.94 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 24 | 24 | 8 | 13 | 4.80 | .301 | 1.28 | 9.2 | 2.4 | 3.9 | 168.2 | 172 | 95 | 90 | 23 | 44 | 73 | 10 | 0 | 0 | 0 | 10 | 2 | 4 | 4.73 |
| RP | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 64 | 0 | 9 | 3 | 2.32 | .282 | 1.15 | 7.2 | 3.2 | 10.3 | 89.1 | 71 | 27 | 23 | 9 | 32 | 102 | 0 | 8 | 4 | 0 | 0 | 2 | 3 | 3.17 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 55 | 0 | 3 | 5 | 4.02 | .270 | 1.10 | 5.9 | 4.0 | 8.1 | 69.1 | 45 | 33 | 31 | 7 | 31 | 62 | 0 | 7 | 3 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Lidge, B.Lidge, Brad # >> | 28 | 2004 | R | 66 | 41 | 0 | 3 | 4 | 5.62 | .320 | 1.37 | 8.8 | 3.7 | 9.4 | 49.2 | 48 | 32 | 31 | 12 | 20 | 51 | 0 | 4 | 0 | 0 | 0 | 2 | 2 | 5.45 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 2 | 2 | 0 | 1 | 5.68 | .255 | 0.95 | 7.5 | 1.5 | 5.3 | 12.2 | 10 | 8 | 8 | 4 | 2 | 7 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.92 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |