| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 7 | 7 | 2 | 4 | 4.06 | .293 | 1.17 | 8.2 | 2.5 | 8.8 | 44.1 | 40 | 25 | 20 | 8 | 12 | 43 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 4.43 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 7 | 7 | 2 | 2 | 5.09 | .325 | 1.44 | 10.5 | 2.6 | 9.0 | 35.1 | 41 | 20 | 20 | 2 | 10 | 35 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 2.60 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 6 | 6 | 0 | 2 | 4.38 | .293 | 1.24 | 8.3 | 2.9 | 5.6 | 37.0 | 34 | 20 | 18 | 1 | 12 | 23 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 3.08 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 6 | 6 | 2 | 1 | 7.04 | .352 | 1.63 | 12.3 | 2.7 | 8.1 | 30.2 | 41 | 25 | 24 | 5 | 9 | 27 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 4.27 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 6 | 6 | 2 | 4 | 4.75 | .329 | 1.44 | 10.3 | 2.8 | 6.8 | 36.0 | 41 | 30 | 19 | 5 | 11 | 27 | 1 | 0 | 0 | 0 | 2 | 1 | 2 | 4.31 |
| SU | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 17 | 0 | 1 | 2 | 4.22 | .281 | 1.13 | 5.6 | 4.7 | 9.0 | 21.1 | 13 | 11 | 10 | 1 | 11 | 21 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.33 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 17 | 0 | 1 | 1 | 4.50 | .298 | 1.23 | 6.5 | 4.5 | 7.8 | 22.0 | 16 | 11 | 11 | 3 | 11 | 19 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.68 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 11 | 0 | 1 | 0 | 5.25 | .379 | 1.83 | 11.3 | 5.3 | 10.5 | 12.0 | 15 | 7 | 7 | 2 | 7 | 14 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 4.58 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 13 | 0 | 0 | 0 | 1.56 | .235 | 0.92 | 6.9 | 1.6 | 7.4 | 17.1 | 13 | 3 | 3 | 1 | 3 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.65 |