| SP | Koufax, S.Koufax, Sandy $$ >> | 30 | 1965 | L | 97 | 34 | 34 | 9 | 18 | 4.76 | .315 | 1.37 | 9.0 | 3.3 | 8.0 | 238.0 | 237 | 129 | 126 | 37 | 88 | 212 | 2 | 0 | 0 | 0 | 18 | 4 | 6 | 4.40 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 32 | 32 | 9 | 16 | 4.59 | .316 | 1.33 | 9.4 | 2.6 | 4.4 | 215.2 | 224 | 116 | 110 | 22 | 63 | 106 | 4 | 0 | 0 | 1 | 16 | 12 | 3 | 4.39 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 31 | 31 | 11 | 18 | 5.37 | .335 | 1.50 | 10.9 | 2.6 | 5.1 | 212.2 | 257 | 139 | 127 | 31 | 62 | 121 | 4 | 0 | 0 | 0 | 16 | 3 | 4 | 4.68 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 79 | 0 | 4 | 2 | 4.18 | .314 | 1.35 | 8.4 | 3.8 | 8.6 | 92.2 | 86 | 44 | 43 | 10 | 39 | 88 | 0 | 1 | 4 | 0 | 0 | 2 | 7 | 3.84 |
| CL | Hader, J.Hader, Josh † $$ >> | 24 | 2018 | L | 93 | 66 | 0 | 5 | 8 | 2.85 | .271 | 1.10 | 4.8 | 5.3 | 8.6 | 72.2 | 38 | 26 | 23 | 1 | 42 | 69 | 0 | 36 | 5 | 0 | 0 | 1 | 0 | 3.06 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 58 | 0 | 2 | 2 | 5.89 | .356 | 1.66 | 11.9 | 3.2 | 9.9 | 62.2 | 82 | 44 | 41 | 13 | 22 | 68 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.60 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 43 | 0 | 3 | 0 | 3.73 | .300 | 1.22 | 7.2 | 4.0 | 9.5 | 50.2 | 40 | 21 | 21 | 7 | 22 | 53 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.20 |