| SP | Buchholz, C.Buchholz, Clay >> | 34 | 2018 | R | 60 | 23 | 23 | 10 | 10 | 4.58 | .299 | 1.25 | 9.0 | 2.2 | 6.3 | 145.1 | 145 | 76 | 74 | 20 | 36 | 102 | 1 | 0 | 0 | 0 | 10 | 5 | 1 | 4.23 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 54 | 23 | 23 | 5 | 8 | 4.42 | .305 | 1.32 | 8.8 | 3.0 | 5.8 | 116.0 | 114 | 57 | 57 | 13 | 39 | 75 | 0 | 0 | 0 | 0 | 8 | 0 | 3 | 4.17 |
| SP | Kelly, M.Kelly, Merrill # >> | 33 | 2022 | R | 50 | 22 | 22 | 5 | 12 | 6.20 | .347 | 1.57 | 10.7 | 3.6 | 5.9 | 114.2 | 135 | 82 | 79 | 17 | 45 | 75 | 0 | 0 | 0 | 0 | 6 | 3 | 3 | 4.89 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2008 | L | 35 | 22 | 22 | 4 | 9 | 6.30 | .363 | 1.66 | 12.2 | 2.9 | 6.2 | 125.2 | 169 | 90 | 88 | 17 | 40 | 86 | 0 | 0 | 0 | 0 | 7 | 6 | 2 | 4.50 |
| SP | Webb, B.Webb, Brandon # >> | 25 | 2004 | R | 21 | 23 | 21 | 4 | 8 | 6.17 | .349 | 1.59 | 9.9 | 4.5 | 6.1 | 116.2 | 127 | 83 | 80 | 12 | 58 | 78 | 0 | 0 | 0 | 0 | 8 | 3 | 2 | 4.58 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 47 | 73 | 0 | 1 | 8 | 4.56 | .344 | 1.53 | 8.6 | 5.2 | 8.0 | 98.2 | 94 | 51 | 50 | 8 | 57 | 87 | 0 | 1 | 5 | 0 | 0 | 4 | 4 | 4.15 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 41 | 65 | 0 | 4 | 6 | 3.09 | .263 | 1.07 | 6.9 | 2.7 | 4.6 | 96.0 | 74 | 34 | 33 | 8 | 29 | 49 | 0 | 6 | 4 | 0 | 0 | 0 | 4 | 3.97 |
| RP | Valverde, J.Valverde, Jose >> | 28 | 2007 | R | 39 | 60 | 0 | 5 | 3 | 3.79 | .292 | 1.21 | 7.5 | 3.5 | 8.4 | 80.2 | 67 | 34 | 34 | 8 | 31 | 75 | 0 | 7 | 0 | 0 | 0 | 2 | 2 | 3.66 |
| RP | Bradley, A.Bradley, Archie >> | 24 | 2017 | R | 36 | 50 | 0 | 3 | 3 | 2.87 | .261 | 1.06 | 7.0 | 2.5 | 7.3 | 69.0 | 54 | 22 | 22 | 6 | 19 | 56 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Villarreal, O.Villarreal, Oscar >> | 22 | 2003 | R | 27 | 31 | 0 | 2 | 1 | 4.38 | .347 | 1.57 | 9.7 | 4.4 | 4.9 | 37.0 | 40 | 19 | 18 | 3 | 18 | 20 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.51 |