| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 27 | 27 | 11 | 10 | 3.46 | .284 | 1.15 | 8.4 | 2.0 | 5.4 | 179.2 | 168 | 75 | 69 | 9 | 39 | 107 | 9 | 0 | 0 | 2 | 16 | 7 | 1 | 3.23 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 74 | 25 | 25 | 11 | 8 | 3.49 | .262 | 1.03 | 7.1 | 2.2 | 6.6 | 170.1 | 135 | 70 | 66 | 23 | 41 | 124 | 3 | 0 | 0 | 0 | 16 | 5 | 3 | 4.11 |
| SP | Morton, C.Morton, Charlie >> | 38 | 2021 | R | 76 | 26 | 26 | 10 | 12 | 5.08 | .325 | 1.41 | 9.6 | 3.1 | 8.2 | 133.0 | 142 | 81 | 75 | 9 | 46 | 121 | 0 | 0 | 0 | 0 | 10 | 4 | 3 | 3.19 |
| SP | Whitney, J.Whitney, Jim >> | 27 | 1884 | R | 81 | 25 | 25 | 13 | 10 | 3.15 | .281 | 1.16 | 8.8 | 1.7 | 5.4 | 191.2 | 186 | 83 | 67 | 17 | 36 | 115 | 14 | 0 | 0 | 3 | 16 | 3 | 5 | 3.57 |
| SP | Anderson, I.Anderson, Ian >> | 22 | 2020 | R | 79 | 25 | 25 | 0 | 2 | 4.08 | .307 | 1.31 | 7.6 | 4.2 | 7.3 | 64.0 | 54 | 29 | 29 | 8 | 30 | 52 | 0 | 0 | 0 | 0 | 0 | 1 | 10 | 4.45 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 68 | 0 | 4 | 3 | 2.82 | .241 | 0.94 | 5.6 | 2.9 | 11.3 | 89.1 | 55 | 28 | 28 | 5 | 29 | 112 | 0 | 5 | 1 | 0 | 0 | 1 | 6 | 2.22 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 87 | 59 | 0 | 4 | 2 | 3.93 | .306 | 1.33 | 7.0 | 5.0 | 8.5 | 68.2 | 53 | 30 | 30 | 9 | 38 | 64 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 4.51 |
| RP | Soriano, R.Soriano, Rafael >> | 28 | 2007 | R | 76 | 49 | 0 | 4 | 1 | 3.79 | .308 | 1.28 | 8.2 | 3.5 | 6.2 | 54.2 | 49 | 28 | 23 | 8 | 21 | 37 | 0 | 6 | 0 | 0 | 0 | 3 | 0 | 4.89 |
| RP | Minter, A.Minter, A.J. >> | 28 | 2022 | L | 67 | 38 | 0 | 0 | 3 | 5.28 | .307 | 1.29 | 8.4 | 3.3 | 9.2 | 44.1 | 41 | 26 | 26 | 2 | 16 | 45 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 2.77 |
| RP | Jimenez, J.Jimenez, Joe >> | 29 | 2024 | R | 61 | 34 | 0 | 4 | 0 | 3.15 | .318 | 1.35 | 7.9 | 4.3 | 8.1 | 40.0 | 35 | 17 | 14 | 5 | 19 | 36 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 4.40 |
| RP | Beachy, B.Beachy, Brandon >> | 25 | 2012 | R | 65 | 48 | 0 | 12 | 4 | 3.88 | .307 | 1.31 | 7.8 | 4.0 | 5.4 | 109.0 | 94 | 51 | 47 | 12 | 49 | 66 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 4.62 |