| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 98 | 9 | 9 | 6 | 1 | 1.64 | .260 | 1.06 | 6.6 | 3.0 | 5.0 | 76.2 | 56 | 27 | 14 | 6 | 25 | 42 | 4 | 0 | 0 | 2 | 8 | 0 | 1 | 3.91 |
| SP | Wilhelm, H.Wilhelm, Hoyt >> | 36 | 1958 | R | 95 | 9 | 9 | 0 | 3 | 2.30 | .226 | 0.84 | 5.0 | 2.7 | 5.7 | 27.1 | 15 | 9 | 7 | 1 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.22 |
| SP | Weilman, C.Weilman, Carl >> | 23 | 1912 | L | 74 | 9 | 9 | 0 | 2 | 4.67 | .297 | 1.21 | 10.6 | 0.5 | 6.4 | 17.1 | 20 | 12 | 9 | 2 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.47 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 72 | 9 | 9 | 2 | 6 | 5.95 | .321 | 1.42 | 9.4 | 3.4 | 9.9 | 42.1 | 44 | 28 | 28 | 7 | 16 | 46 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.12 |
| RP | Uehara, K.Uehara, Koji >> | 36 | 2011 | R | 99 | 18 | 0 | 2 | 2 | 2.74 | .289 | 1.22 | 9.4 | 1.6 | 9.0 | 23.0 | 24 | 14 | 7 | 4 | 4 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.78 |
| RP | Bautista, F.Bautista, Felix >> | 28 | 2023 | R | 84 | 22 | 0 | 4 | 4 | 4.91 | .369 | 1.75 | 9.7 | 6.5 | 8.6 | 25.2 | 27 | 16 | 14 | 2 | 18 | 24 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 4.28 |
| RP | Givens, M.Givens, Mychal >> | 25 | 2015 | R | 75 | 19 | 0 | 0 | 0 | 3.38 | .241 | 0.92 | 5.6 | 2.8 | 8.7 | 29.1 | 18 | 12 | 11 | 2 | 9 | 28 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.00 |
| RP | O'Day, D.O'Day, Darren >> | 33 | 2015 | R | 68 | 14 | 0 | 2 | 0 | 1.26 | .306 | 1.26 | 7.7 | 3.9 | 7.1 | 14.1 | 12 | 2 | 2 | 0 | 6 | 11 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.93 |
| RP | Benitez, A.Benitez, Armando >> | 25 | 1997 | R | 44 | 15 | 0 | 0 | 2 | 2.84 | .260 | 1.00 | 6.6 | 2.4 | 9.0 | 19.0 | 14 | 7 | 6 | 1 | 5 | 19 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.63 |
| RP | Bradish, K.Bradish, Kyle >> | 27 | 2024 | R | 55 | 16 | 0 | 5 | 0 | 3.11 | .298 | 1.27 | 5.8 | 5.8 | 10.7 | 37.2 | 24 | 14 | 13 | 2 | 24 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.27 |