| SP | Koufax, S.Koufax, Sandy † $ >> | 30 | 1965 | L | 97 | 33 | 33 | 14 | 12 | 3.02 | .285 | 1.17 | 7.5 | 3.1 | 8.2 | 232.2 | 193 | 89 | 78 | 13 | 79 | 212 | 3 | 0 | 0 | 2 | 20 | 6 | 2 | 3.00 |
| SP | Gibson, B.Gibson, Bob $ >> | 33 | 1968 | R | 93 | 33 | 33 | 13 | 14 | 3.66 | .298 | 1.26 | 8.8 | 2.6 | 5.6 | 238.2 | 232 | 102 | 97 | 23 | 69 | 149 | 9 | 0 | 0 | 2 | 19 | 3 | 7 | 3.91 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 32 | 32 | 10 | 14 | 5.82 | .339 | 1.52 | 9.1 | 4.5 | 7.6 | 188.2 | 191 | 132 | 122 | 20 | 95 | 158 | 0 | 0 | 0 | 0 | 11 | 4 | 3 | 4.28 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 32 | 32 | 19 | 11 | 4.06 | .285 | 1.16 | 7.9 | 2.6 | 4.2 | 221.2 | 194 | 110 | 100 | 20 | 64 | 103 | 6 | 0 | 0 | 2 | 20 | 7 | 2 | 4.21 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 31 | 11 | 14 | 6.11 | .344 | 1.54 | 11.0 | 2.8 | 4.7 | 190.0 | 233 | 138 | 129 | 37 | 60 | 100 | 3 | 1 | 0 | 0 | 10 | 6 | 5 | 5.52 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 61 | 0 | 2 | 7 | 4.48 | .313 | 1.36 | 8.6 | 3.8 | 9.6 | 62.1 | 59 | 31 | 31 | 5 | 26 | 66 | 0 | 39 | 3 | 0 | 0 | 0 | 1 | 3.18 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 59 | 0 | 0 | 1 | 3.92 | .277 | 1.15 | 6.6 | 3.8 | 8.2 | 64.1 | 47 | 28 | 28 | 8 | 27 | 58 | 0 | 5 | 3 | 0 | 0 | 0 | 1 | 4.08 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 72 | 0 | 6 | 3 | 4.11 | .288 | 1.17 | 7.7 | 3.0 | 11.0 | 76.2 | 65 | 36 | 35 | 8 | 25 | 93 | 0 | 3 | 2 | 0 | 0 | 3 | 3 | 3.03 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 40 | 0 | 1 | 1 | 2.65 | .356 | 1.55 | 10.7 | 3.4 | 7.3 | 37.1 | 44 | 13 | 11 | 3 | 14 | 30 | 0 | 1 | 1 | 0 | 0 | 4 | 0 | 3.89 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 32 | 0 | 2 | 0 | 3.44 | .286 | 1.20 | 6.8 | 4.3 | 8.3 | 36.2 | 27 | 14 | 14 | 6 | 17 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 19 | 0 | 4 | 2 | 3.39 | .312 | 1.36 | 8.9 | 3.4 | 6.3 | 82.1 | 81 | 37 | 31 | 9 | 31 | 57 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4.17 |