| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 16 | 16 | 8 | 4 | 3.05 | .284 | 1.17 | 7.7 | 2.8 | 5.5 | 133.0 | 114 | 53 | 45 | 15 | 41 | 82 | 3 | 0 | 0 | 0 | 11 | 3 | 2 | 4.23 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 16 | 16 | 4 | 8 | 6.22 | .335 | 1.50 | 10.2 | 3.4 | 8.6 | 92.2 | 104 | 66 | 64 | 19 | 35 | 88 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.95 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 16 | 16 | 6 | 8 | 5.86 | .331 | 1.49 | 10.4 | 3.0 | 5.9 | 109.0 | 126 | 74 | 71 | 21 | 36 | 71 | 3 | 0 | 0 | 0 | 5 | 0 | 2 | 5.19 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 16 | 16 | 4 | 11 | 5.52 | .340 | 1.51 | 10.9 | 2.7 | 4.2 | 109.1 | 132 | 72 | 67 | 11 | 33 | 51 | 4 | 0 | 0 | 1 | 6 | 4 | 1 | 4.39 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 16 | 16 | 4 | 8 | 6.80 | .374 | 1.76 | 11.5 | 4.3 | 4.2 | 82.0 | 105 | 67 | 62 | 11 | 39 | 38 | 0 | 0 | 0 | 0 | 5 | 3 | 3 | 5.35 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 42 | 0 | 4 | 1 | 3.08 | .317 | 1.35 | 6.1 | 6.2 | 9.0 | 49.2 | 33 | 18 | 17 | 6 | 34 | 49 | 0 | 6 | 3 | 0 | 0 | 2 | 3 | 4.80 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 39 | 0 | 4 | 0 | 4.00 | .341 | 1.56 | 7.8 | 6.2 | 8.4 | 45.0 | 39 | 26 | 20 | 4 | 31 | 42 | 0 | 5 | 0 | 0 | 0 | 0 | 2 | 4.36 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 29 | 0 | 1 | 0 | 2.95 | .267 | 1.09 | 5.8 | 4.3 | 12.0 | 36.2 | 23 | 12 | 12 | 4 | 17 | 48 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.19 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 18 | 0 | 1 | 2 | 5.65 | .381 | 1.78 | 10.9 | 5.5 | 9.6 | 28.2 | 34 | 20 | 18 | 5 | 17 | 30 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.21 |
| RP | Williamson, S.Williamson, Scott >> | 23 | 1999 | R | 45 | 20 | 0 | 0 | 0 | 6.05 | .363 | 1.71 | 8.5 | 7.1 | 9.0 | 19.1 | 18 | 15 | 13 | 0 | 15 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.37 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 6 | 0 | 1 | 1 | 3.60 | .268 | 1.10 | 9.9 | 0.0 | 0.9 | 10.0 | 11 | 4 | 4 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.10 |