| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 20 | 20 | 6 | 8 | 4.13 | .305 | 1.28 | 8.0 | 3.5 | 8.5 | 130.2 | 116 | 60 | 60 | 18 | 51 | 123 | 2 | 0 | 0 | 0 | 12 | 5 | 2 | 4.20 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 19 | 19 | 2 | 8 | 6.36 | .363 | 1.69 | 11.0 | 4.2 | 9.2 | 75.0 | 92 | 53 | 53 | 13 | 35 | 77 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.64 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 62 | 19 | 18 | 5 | 9 | 5.01 | .343 | 1.50 | 8.8 | 4.9 | 10.3 | 109.2 | 106 | 63 | 61 | 13 | 59 | 125 | 0 | 0 | 0 | 0 | 7 | 7 | 9 | 4.07 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 92 | 59 | 0 | 1 | 2 | 4.02 | .336 | 1.51 | 7.7 | 6.0 | 11.0 | 71.2 | 61 | 32 | 32 | 9 | 47 | 87 | 0 | 5 | 1 | 0 | 0 | 1 | 9 | 4.23 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 54 | 0 | 7 | 5 | 5.54 | .352 | 1.57 | 7.9 | 6.2 | 11.9 | 65.0 | 57 | 43 | 40 | 6 | 45 | 86 | 0 | 2 | 2 | 0 | 0 | 4 | 8 | 3.82 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 59 | 50 | 0 | 2 | 3 | 5.53 | .340 | 1.53 | 8.4 | 5.4 | 10.7 | 57.0 | 53 | 41 | 35 | 11 | 34 | 68 | 0 | 3 | 4 | 0 | 0 | 1 | 1 | 4.96 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 40 | 35 | 0 | 1 | 3 | 3.91 | .316 | 1.37 | 9.0 | 3.4 | 7.3 | 48.1 | 48 | 22 | 21 | 7 | 18 | 39 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.46 |