| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 19 | 19 | 9 | 6 | 3.30 | .280 | 1.14 | 7.9 | 2.4 | 10.4 | 128.1 | 112 | 48 | 47 | 14 | 34 | 148 | 1 | 0 | 0 | 0 | 15 | 4 | 0 | 3.00 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 92 | 19 | 19 | 5 | 7 | 4.97 | .326 | 1.44 | 9.4 | 3.6 | 9.6 | 112.1 | 117 | 65 | 62 | 23 | 45 | 119 | 1 | 0 | 0 | 0 | 10 | 1 | 6 | 4.78 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 18 | 18 | 8 | 4 | 3.07 | .314 | 1.34 | 6.8 | 5.3 | 8.0 | 120.1 | 91 | 44 | 41 | 10 | 70 | 107 | 1 | 0 | 0 | 0 | 14 | 4 | 2 | 4.15 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 37 | 0 | 2 | 1 | 2.97 | .310 | 1.35 | 8.3 | 4.0 | 9.8 | 36.1 | 33 | 13 | 12 | 1 | 16 | 39 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.53 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 25 | 0 | 2 | 0 | 4.08 | .317 | 1.36 | 8.0 | 4.5 | 10.6 | 28.2 | 25 | 13 | 13 | 4 | 14 | 33 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.11 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 16 | 0 | 2 | 1 | 4.15 | .307 | 1.33 | 6.9 | 5.3 | 11.6 | 17.1 | 13 | 12 | 8 | 1 | 10 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.94 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 19 | 0 | 0 | 0 | 6.64 | .378 | 1.82 | 9.0 | 7.7 | 12.6 | 20.1 | 20 | 18 | 15 | 4 | 17 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.35 |
| SP | Hershiser, O.Hershiser, Orel >> | 30 | 1988 | R | 44 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Kimbrel, C.Kimbrel, Craig † $ >> | 24 | 2012 | R | 100 | 38 | 0 | 4 | 4 | 3.46 | .273 | 1.10 | 6.2 | 3.7 | 10.8 | 39.0 | 27 | 16 | 15 | 6 | 16 | 47 | 0 | 23 | 3 | 0 | 0 | 1 | 2 | 3.90 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 92 | 41 | 0 | 1 | 3 | 3.22 | .306 | 1.32 | 7.5 | 4.5 | 10.8 | 36.1 | 30 | 17 | 13 | 6 | 18 | 43 | 0 | 4 | 7 | 0 | 0 | 0 | 2 | 4.28 |