| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 18 | 18 | 3 | 11 | 6.68 | .341 | 1.52 | 9.9 | 3.9 | 9.0 | 103.2 | 113 | 84 | 77 | 22 | 45 | 103 | 1 | 0 | 0 | 0 | 6 | 3 | 7 | 5.17 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 18 | 18 | 8 | 5 | 3.61 | .313 | 1.32 | 8.7 | 3.3 | 6.4 | 99.2 | 96 | 40 | 40 | 8 | 36 | 70 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 3.85 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 76 | 18 | 18 | 6 | 7 | 4.72 | .303 | 1.27 | 8.3 | 3.2 | 7.4 | 124.0 | 114 | 66 | 65 | 19 | 44 | 102 | 3 | 0 | 0 | 1 | 9 | 4 | 3 | 4.51 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 74 | 18 | 18 | 10 | 6 | 4.30 | .307 | 1.28 | 8.1 | 3.4 | 6.4 | 115.0 | 104 | 56 | 55 | 7 | 43 | 82 | 1 | 0 | 0 | 0 | 9 | 6 | 3 | 3.64 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 46 | 0 | 2 | 1 | 2.51 | .238 | 0.92 | 6.2 | 2.2 | 9.9 | 71.2 | 49 | 23 | 20 | 12 | 17 | 78 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 3.76 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 49 | 0 | 3 | 0 | 3.65 | .292 | 1.22 | 6.9 | 4.2 | 10.0 | 56.2 | 43 | 30 | 23 | 6 | 26 | 62 | 0 | 9 | 3 | 0 | 0 | 1 | 0 | 3.63 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 44 | 0 | 2 | 3 | 3.14 | .308 | 1.32 | 9.8 | 2.3 | 9.0 | 48.2 | 52 | 22 | 17 | 4 | 12 | 48 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.90 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 63 | 27 | 0 | 0 | 1 | 4.33 | .341 | 1.52 | 11.3 | 2.3 | 9.0 | 27.0 | 34 | 16 | 13 | 4 | 7 | 27 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 3.81 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 55 | 26 | 0 | 2 | 2 | 6.49 | .336 | 1.44 | 7.3 | 5.9 | 9.7 | 26.1 | 21 | 19 | 19 | 5 | 17 | 28 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 5.54 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |