| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 16 | 16 | 7 | 5 | 3.36 | .311 | 1.34 | 9.3 | 2.7 | 10.3 | 107.0 | 111 | 49 | 40 | 15 | 32 | 122 | 1 | 0 | 0 | 0 | 11 | 2 | 5 | 3.50 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 15 | 15 | 5 | 8 | 6.61 | .338 | 1.49 | 9.8 | 3.8 | 8.6 | 81.2 | 88 | 60 | 60 | 17 | 34 | 77 | 0 | 0 | 0 | 0 | 5 | 3 | 7 | 5.20 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 85 | 15 | 15 | 5 | 8 | 5.55 | .307 | 1.29 | 9.5 | 2.1 | 6.9 | 94.0 | 99 | 59 | 58 | 18 | 22 | 72 | 3 | 0 | 0 | 0 | 7 | 4 | 1 | 4.79 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 15 | 15 | 5 | 5 | 5.59 | .329 | 1.46 | 8.9 | 4.3 | 8.9 | 96.2 | 95 | 61 | 60 | 23 | 46 | 95 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 5.60 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 16 | 15 | 4 | 7 | 6.89 | .378 | 1.83 | 11.0 | 5.5 | 6.8 | 78.1 | 95 | 66 | 60 | 16 | 48 | 59 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 6.00 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 87 | 28 | 0 | 1 | 1 | 3.38 | .307 | 1.26 | 7.1 | 4.3 | 10.2 | 29.1 | 23 | 11 | 11 | 3 | 14 | 33 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 3.72 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 43 | 0 | 5 | 2 | 3.10 | .269 | 1.10 | 7.1 | 2.8 | 10.2 | 58.0 | 46 | 20 | 20 | 2 | 18 | 66 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.10 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 32 | 0 | 1 | 2 | 2.27 | .222 | 0.86 | 5.3 | 2.5 | 10.2 | 39.2 | 23 | 10 | 10 | 6 | 11 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.59 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 22 | 0 | 4 | 0 | 3.80 | .290 | 1.23 | 5.9 | 5.5 | 9.8 | 23.2 | 15 | 10 | 10 | 3 | 14 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 4 | 4.35 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 16 | 0 | 1 | 0 | 7.85 | .329 | 1.47 | 10.0 | 3.5 | 10.0 | 18.1 | 20 | 16 | 16 | 5 | 7 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.56 |