| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 20 | 20 | 12 | 6 | 3.00 | .261 | 1.02 | 6.8 | 2.3 | 6.7 | 150.0 | 114 | 50 | 50 | 16 | 39 | 112 | 2 | 0 | 0 | 1 | 14 | 6 | 1 | 3.79 |
| SP | Snell, B.Snell, Blake # $ >> | 25 | 2018 | L | 89 | 19 | 19 | 8 | 7 | 4.85 | .291 | 1.21 | 7.7 | 3.3 | 10.1 | 105.2 | 90 | 57 | 57 | 18 | 38 | 118 | 0 | 0 | 0 | 0 | 9 | 2 | 5 | 4.12 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 16 | 16 | 9 | 3 | 5.28 | .341 | 1.53 | 8.9 | 4.9 | 7.3 | 92.0 | 91 | 54 | 54 | 12 | 50 | 75 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 4.76 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 50 | 0 | 3 | 1 | 2.60 | .264 | 1.05 | 5.6 | 3.9 | 9.1 | 72.2 | 45 | 23 | 21 | 7 | 31 | 73 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.61 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 15 | 0 | 3 | 1 | 4.22 | .319 | 1.41 | 4.5 | 9.0 | 8.1 | 10.2 | 5 | 5 | 5 | 1 | 10 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.50 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 68 | 8 | 0 | 0 | 1 | 4.70 | .343 | 1.57 | 11.6 | 3.9 | 7.7 | 7.2 | 9 | 4 | 4 | 2 | 3 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.29 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 12 | 0 | 2 | 0 | 3.33 | .299 | 1.26 | 8.2 | 3.1 | 6.5 | 46.0 | 42 | 17 | 17 | 4 | 16 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.80 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 39 | 0 | 0 | 1 | 1.78 | .203 | 0.76 | 4.1 | 2.8 | 13.1 | 35.1 | 16 | 7 | 7 | 4 | 11 | 51 | 0 | 37 | 2 | 0 | 0 | 0 | 2 | 2.51 |