| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 11 | 11 | 4 | 3 | 4.39 | .299 | 1.28 | 8.9 | 2.7 | 6.4 | 69.2 | 68 | 35 | 34 | 8 | 21 | 49 | 3 | 0 | 0 | 0 | 6 | 0 | 1 | 4.00 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 74 | 11 | 11 | 3 | 4 | 3.07 | .279 | 1.16 | 7.4 | 3.1 | 7.6 | 58.2 | 48 | 20 | 20 | 5 | 20 | 49 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.47 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 55 | 11 | 11 | 4 | 4 | 7.04 | .374 | 1.73 | 12.4 | 3.4 | 5.9 | 53.2 | 73 | 44 | 42 | 8 | 20 | 35 | 1 | 0 | 0 | 1 | 3 | 3 | 3 | 4.94 |
| SP | Willis, D.Willis, Dontrelle # >> | 23 | 2005 | L | 49 | 10 | 10 | 2 | 3 | 5.40 | .314 | 1.37 | 10.4 | 2.0 | 5.7 | 63.1 | 73 | 38 | 38 | 9 | 14 | 40 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.25 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 96 | 29 | 0 | 2 | 1 | 4.43 | .304 | 1.27 | 7.9 | 3.6 | 10.1 | 42.2 | 37 | 21 | 21 | 5 | 17 | 47 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.67 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 25 | 0 | 1 | 0 | 3.86 | .313 | 1.36 | 7.2 | 5.4 | 9.4 | 25.2 | 20 | 11 | 11 | 2 | 15 | 26 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 3.76 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 46 | 20 | 0 | 2 | 0 | 3.12 | .284 | 1.15 | 5.9 | 4.5 | 6.9 | 26.0 | 17 | 9 | 9 | 0 | 13 | 20 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.08 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 33 | 19 | 0 | 0 | 2 | 4.63 | .333 | 1.50 | 9.0 | 4.7 | 10.6 | 23.1 | 23 | 13 | 12 | 4 | 12 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.48 |
| SP | Washburn, J.Washburn, Jarrod >> | 28 | 2002 | L | 32 | 15 | 0 | 3 | 4 | 6.99 | .366 | 1.73 | 11.3 | 4.5 | 7.1 | 28.1 | 35 | 25 | 22 | 6 | 14 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.71 |