| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 99 | 29 | 29 | 10 | 12 | 3.40 | .311 | 1.33 | 8.4 | 3.6 | 8.9 | 212.0 | 198 | 83 | 80 | 18 | 84 | 209 | 3 | 0 | 0 | 0 | 19 | 5 | 4 | 3.39 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 28 | 28 | 1 | 7 | 4.57 | .341 | 1.50 | 9.3 | 4.3 | 6.3 | 108.1 | 112 | 58 | 55 | 14 | 51 | 76 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 4.83 |
| SP | Young, C.Young, Chris † >> | 28 | 2007 | R | 83 | 28 | 28 | 15 | 8 | 3.19 | .293 | 1.22 | 7.3 | 3.7 | 6.4 | 178.0 | 144 | 67 | 63 | 12 | 74 | 127 | 0 | 0 | 0 | 0 | 17 | 3 | 3 | 3.75 |
| SP | Park, C.Park, Chan Ho # >> | 28 | 2001 | R | 60 | 28 | 28 | 10 | 9 | 5.19 | .345 | 1.54 | 9.8 | 4.1 | 7.7 | 177.0 | 192 | 105 | 102 | 33 | 80 | 152 | 0 | 0 | 0 | 0 | 12 | 8 | 2 | 5.20 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 55 | 26 | 26 | 9 | 9 | 5.12 | .346 | 1.54 | 9.6 | 4.3 | 9.0 | 165.1 | 176 | 98 | 94 | 25 | 79 | 165 | 1 | 0 | 0 | 0 | 14 | 7 | 7 | 4.53 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 73 | 0 | 10 | 2 | 3.34 | .293 | 1.23 | 8.7 | 2.4 | 9.4 | 107.2 | 104 | 42 | 40 | 11 | 28 | 112 | 0 | 4 | 3 | 0 | 0 | 2 | 0 | 3.08 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 72 | 0 | 5 | 6 | 4.45 | .309 | 1.31 | 7.0 | 4.8 | 10.9 | 97.0 | 75 | 49 | 48 | 13 | 52 | 117 | 0 | 10 | 4 | 0 | 0 | 3 | 3 | 4.03 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 58 | 0 | 2 | 6 | 4.52 | .306 | 1.27 | 7.6 | 3.9 | 9.5 | 71.2 | 60 | 41 | 36 | 12 | 31 | 75 | 0 | 5 | 3 | 0 | 0 | 4 | 0 | 4.56 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 45 | 49 | 0 | 2 | 7 | 6.88 | .359 | 1.66 | 10.9 | 4.2 | 5.9 | 53.2 | 64 | 43 | 41 | 17 | 25 | 35 | 0 | 10 | 6 | 0 | 0 | 1 | 1 | 7.32 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 34 | 43 | 0 | 2 | 1 | 2.87 | .288 | 1.21 | 6.1 | 4.8 | 9.6 | 47.0 | 32 | 15 | 15 | 4 | 25 | 50 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.57 |
| SP | Washburn, J.Washburn, Jarrod >> | 28 | 2002 | L | 33 | 1 | 0 | 0 | 0 | 0.00 | .800 | 12.00 | - | - | - | 0.1 | 2 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 44 | 16 | 0 | 2 | 4 | 5.03 | .354 | 1.62 | 10.6 | 4.0 | 11.4 | 34.0 | 40 | 21 | 19 | 8 | 15 | 43 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.94 |