| SP | Johnson, R.Johnson, Randy † >> | 38 | 2001 | L | 97 | 29 | 29 | 13 | 10 | 3.32 | .315 | 1.34 | 9.0 | 3.0 | 10.5 | 214.1 | 215 | 87 | 79 | 19 | 72 | 250 | 5 | 0 | 0 | 3 | 19 | 9 | 4 | 2.95 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 82 | 28 | 28 | 15 | 9 | 3.72 | .304 | 1.29 | 9.0 | 2.7 | 6.5 | 205.2 | 205 | 91 | 85 | 29 | 61 | 148 | 5 | 0 | 0 | 0 | 16 | 4 | 6 | 4.35 |
| SP | Williams, W.Williams, Woody # >> | 36 | 2002 | R | 79 | 28 | 28 | 8 | 10 | 4.68 | .299 | 1.24 | 9.3 | 1.8 | 6.5 | 177.0 | 183 | 97 | 92 | 29 | 36 | 128 | 1 | 0 | 0 | 0 | 13 | 8 | 2 | 4.43 |
| SP | Santana, E.Santana, Ervin # >> | 25 | 2008 | R | 55 | 28 | 28 | 7 | 13 | 5.06 | .327 | 1.44 | 9.9 | 3.1 | 7.3 | 170.2 | 187 | 99 | 96 | 30 | 59 | 138 | 0 | 0 | 0 | 0 | 11 | 3 | 5 | 4.76 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 49 | 27 | 27 | 7 | 13 | 6.04 | .358 | 1.64 | 10.9 | 3.9 | 6.9 | 170.0 | 206 | 127 | 114 | 34 | 73 | 131 | 1 | 0 | 0 | 0 | 9 | 6 | 5 | 5.45 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 53 | 51 | 0 | 3 | 2 | 3.82 | .300 | 1.24 | 8.0 | 3.2 | 4.9 | 61.1 | 54 | 28 | 26 | 6 | 22 | 33 | 0 | 7 | 3 | 0 | 0 | 3 | 0 | 4.43 |
| RP | Fuentes, B.Fuentes, Brian >> | 33 | 2008 | L | 33 | 28 | 0 | 3 | 2 | 8.00 | .400 | 1.93 | 11.3 | 6.0 | 6.0 | 27.0 | 34 | 25 | 24 | 5 | 18 | 18 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 6.30 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Verlander, J.Verlander, Justin >> | 26 | 2009 | R | 44 | 5 | 0 | 1 | 2 | 2.08 | .291 | 1.23 | 6.9 | 4.2 | 7.6 | 13.0 | 10 | 4 | 3 | 1 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.69 |