| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 100 | 29 | 29 | 9 | 11 | 4.08 | .280 | 1.16 | 8.8 | 1.6 | 9.5 | 176.1 | 173 | 82 | 80 | 26 | 31 | 186 | 3 | 0 | 0 | 1 | 16 | 2 | 4 | 3.37 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 87 | 29 | 29 | 6 | 7 | 5.24 | .318 | 1.37 | 9.1 | 3.3 | 8.4 | 159.2 | 160 | 93 | 93 | 23 | 58 | 149 | 1 | 0 | 0 | 0 | 12 | 5 | 3 | 4.19 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 85 | 26 | 26 | 8 | 11 | 4.41 | .302 | 1.28 | 9.2 | 2.3 | 6.7 | 159.1 | 163 | 83 | 78 | 24 | 41 | 118 | 0 | 0 | 0 | 0 | 15 | 3 | 2 | 4.31 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 28 | 27 | 10 | 8 | 5.56 | .335 | 1.48 | 10.4 | 2.9 | 5.4 | 149.0 | 173 | 95 | 92 | 25 | 48 | 89 | 0 | 0 | 0 | 0 | 13 | 4 | 1 | 5.03 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 26 | 26 | 12 | 7 | 6.22 | .353 | 1.59 | 10.2 | 4.1 | 6.6 | 140.1 | 159 | 97 | 97 | 25 | 64 | 103 | 1 | 0 | 0 | 0 | 7 | 7 | 4 | 5.37 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 96 | 74 | 0 | 7 | 3 | 2.79 | .238 | 0.94 | 6.6 | 1.8 | 9.6 | 113.0 | 83 | 35 | 35 | 11 | 23 | 121 | 0 | 14 | 4 | 0 | 0 | 0 | 0 | 2.73 |
| RP | Wagner, B.Wagner, Billy † >> | 32 | 2003 | L | 89 | 72 | 0 | 9 | 6 | 3.23 | .262 | 1.03 | 5.5 | 3.9 | 8.3 | 97.2 | 59 | 37 | 35 | 8 | 42 | 89 | 0 | 7 | 5 | 0 | 0 | 3 | 5 | 3.63 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 85 | 55 | 0 | 6 | 1 | 3.21 | .286 | 1.17 | 7.2 | 3.4 | 6.0 | 61.2 | 49 | 22 | 22 | 7 | 23 | 41 | 0 | 5 | 0 | 0 | 0 | 2 | 6 | 4.38 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 44 | 0 | 5 | 1 | 5.09 | .312 | 1.32 | 9.3 | 2.5 | 10.0 | 53.0 | 55 | 30 | 30 | 8 | 15 | 59 | 0 | 4 | 4 | 0 | 0 | 2 | 2 | 3.70 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 34 | 0 | 3 | 3 | 3.99 | .350 | 1.57 | 11.4 | 2.8 | 8.8 | 38.1 | 48 | 18 | 17 | 4 | 12 | 37 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.53 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 28 | 0 | 3 | 0 | 1.30 | .175 | 0.63 | 4.0 | 1.9 | 7.4 | 34.2 | 15 | 5 | 5 | 3 | 7 | 28 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 3.12 |