| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 11 | 11 | 1 | 5 | 5.94 | .364 | 1.72 | 10.9 | 4.6 | 7.0 | 53.0 | 64 | 36 | 35 | 9 | 27 | 41 | 0 | 0 | 0 | 0 | 5 | 0 | 2 | 5.19 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 77 | 10 | 10 | 2 | 2 | 7.36 | .367 | 1.68 | 12.1 | 3.3 | 8.8 | 47.2 | 63 | 39 | 39 | 5 | 17 | 46 | 1 | 0 | 0 | 0 | 4 | 3 | 1 | 3.70 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 11 | 10 | 3 | 6 | 6.34 | .320 | 1.39 | 10.6 | 2.0 | 6.5 | 55.1 | 65 | 42 | 39 | 14 | 12 | 40 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.56 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 11 | 10 | 3 | 2 | 3.43 | .270 | 1.10 | 6.8 | 3.2 | 6.2 | 65.2 | 49 | 27 | 25 | 8 | 23 | 45 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 4.32 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 95 | 35 | 0 | 3 | 2 | 5.24 | .302 | 1.25 | 9.0 | 2.3 | 11.9 | 46.1 | 46 | 27 | 27 | 6 | 12 | 61 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 2.96 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 34 | 0 | 5 | 1 | 5.68 | .349 | 1.61 | 10.2 | 4.6 | 10.2 | 31.2 | 35 | 20 | 20 | 6 | 16 | 35 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 4.81 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 29 | 0 | 2 | 2 | 4.15 | .302 | 1.27 | 8.7 | 2.9 | 9.0 | 34.2 | 33 | 20 | 16 | 4 | 11 | 34 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.59 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 79 | 25 | 0 | 1 | 1 | 2.60 | .302 | 1.27 | 6.9 | 4.8 | 8.2 | 34.2 | 26 | 10 | 10 | 4 | 18 | 31 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.38 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 35 | 0 | 2 | 0 | 7.51 | .416 | 2.14 | 13.0 | 6.4 | 11.1 | 38.1 | 55 | 32 | 32 | 12 | 27 | 47 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.76 |