| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 5 | 5 | 1 | 1 | 3.19 | .349 | 1.58 | 10.5 | 4.0 | 8.8 | 36.2 | 42 | 17 | 13 | 5 | 16 | 35 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.28 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 4 | 4 | 2 | 1 | 2.55 | .282 | 1.18 | 7.1 | 3.8 | 7.1 | 24.2 | 19 | 7 | 7 | 4 | 10 | 19 | 1 | 0 | 0 | 1 | 3 | 0 | 0 | 4.83 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 57 | 4 | 4 | 1 | 3 | 5.09 | .343 | 1.52 | 10.2 | 3.5 | 7.4 | 23.0 | 26 | 14 | 13 | 4 | 9 | 19 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 4.91 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 11 | 0 | 2 | 1 | 5.29 | .301 | 1.29 | 10.1 | 1.6 | 13.2 | 17.0 | 19 | 10 | 10 | 3 | 3 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.88 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 8 | 0 | 1 | 0 | 1.86 | .194 | 0.72 | 4.0 | 3.0 | 10.0 | 9.2 | 4 | 2 | 2 | 2 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.67 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 3 | 0 | 0 | 0 | 2.45 | .353 | 1.64 | 6.0 | 12.0 | 12.0 | 3.2 | 2 | 1 | 1 | 1 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.67 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 3 | 0 | 0 | 0 | 4.15 | .316 | 1.38 | 6.8 | 6.8 | 4.5 | 4.1 | 3 | 2 | 2 | 1 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.50 |