| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 11 | 11 | 1 | 9 | 7.82 | .333 | 1.50 | 11.5 | 2.2 | 8.1 | 58.2 | 74 | 52 | 51 | 12 | 14 | 52 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.62 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 10 | 10 | 5 | 3 | 3.76 | .333 | 1.48 | 8.7 | 4.8 | 10.4 | 64.2 | 62 | 36 | 27 | 9 | 34 | 74 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.16 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 10 | 10 | 3 | 5 | 4.76 | .325 | 1.41 | 9.6 | 3.1 | 4.1 | 70.0 | 75 | 45 | 37 | 7 | 24 | 32 | 1 | 0 | 0 | 0 | 3 | 2 | 3 | 4.50 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 10 | 10 | 3 | 6 | 6.45 | .371 | 1.75 | 13.5 | 2.3 | 5.0 | 60.0 | 90 | 53 | 43 | 8 | 15 | 33 | 2 | 0 | 0 | 0 | 3 | 1 | 1 | 4.43 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 11 | 10 | 3 | 7 | 7.34 | .393 | 1.86 | 12.9 | 3.9 | 3.8 | 57.2 | 82 | 51 | 47 | 11 | 25 | 24 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 6.25 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 26 | 0 | 0 | 1 | 3.90 | .297 | 1.27 | 8.7 | 2.8 | 7.0 | 32.1 | 31 | 17 | 14 | 4 | 10 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.00 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 26 | 0 | 0 | 0 | 4.01 | .303 | 1.25 | 8.7 | 2.7 | 7.4 | 33.2 | 32 | 16 | 15 | 4 | 10 | 27 | 0 | 5 | 0 | 0 | 0 | 2 | 0 | 4.03 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 22 | 0 | 2 | 0 | 2.20 | .225 | 0.84 | 6.8 | 1.0 | 10.6 | 28.2 | 21 | 8 | 7 | 1 | 3 | 33 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 1.54 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 10 | 0 | 1 | 0 | 4.05 | .259 | 1.05 | 6.9 | 2.8 | 11.1 | 13.1 | 10 | 9 | 6 | 2 | 4 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.46 |