| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 6 | 9 | 4.35 | .316 | 1.36 | 8.6 | 3.7 | 7.5 | 128.1 | 122 | 68 | 62 | 14 | 53 | 107 | 1 | 0 | 0 | 1 | 12 | 3 | 7 | 4.06 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 19 | 19 | 8 | 7 | 3.48 | .273 | 1.08 | 7.8 | 2.0 | 5.6 | 144.2 | 124 | 63 | 56 | 12 | 32 | 89 | 4 | 0 | 0 | 0 | 12 | 7 | 1 | 3.66 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 19 | 19 | 9 | 7 | 4.98 | .315 | 1.37 | 9.1 | 3.3 | 5.8 | 132.0 | 133 | 78 | 73 | 18 | 48 | 85 | 4 | 0 | 0 | 1 | 9 | 1 | 1 | 4.60 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 19 | 19 | 9 | 4 | 4.78 | .345 | 1.57 | 10.1 | 4.1 | 5.9 | 128.0 | 143 | 71 | 68 | 17 | 58 | 84 | 0 | 0 | 0 | 0 | 11 | 1 | 2 | 4.80 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 44 | 0 | 0 | 3 | 4.55 | .346 | 1.58 | 11.5 | 3.1 | 10.2 | 29.2 | 37 | 15 | 15 | 3 | 10 | 33 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.10 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 24 | 0 | 2 | 1 | 3.00 | .316 | 1.39 | 9.5 | 3.0 | 5.5 | 18.0 | 19 | 7 | 6 | 2 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Charlton, N.Charlton, Norm >> | 30 | 1993 | L | 30 | 42 | 0 | 0 | 4 | 3.04 | .279 | 1.16 | 5.5 | 5.2 | 10.7 | 26.2 | 16 | 11 | 9 | 2 | 15 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.35 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 30 | 0 | 1 | 2 | 1.54 | .278 | 1.16 | 7.0 | 3.5 | 9.8 | 23.1 | 18 | 4 | 4 | 1 | 9 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.57 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 8 | 0 | 0 | 0 | 6.61 | .333 | 1.40 | 10.2 | 2.6 | 4.1 | 31.1 | 35 | 26 | 23 | 6 | 9 | 14 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 5.77 |
| CL | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 88 | 28 | 0 | 0 | 2 | 2.13 | .321 | 1.42 | 10.8 | 2.2 | 9.7 | 25.1 | 30 | 6 | 6 | 0 | 6 | 27 | 0 | 24 | 3 | 0 | 0 | 0 | 0 | 1.56 |