| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 40 | 40 | 24 | 12 | 4.27 | .292 | 1.22 | 9.3 | 1.7 | 8.0 | 282.2 | 291 | 146 | 134 | 32 | 54 | 252 | 5 | 0 | 0 | 1 | 21 | 4 | 4 | 3.30 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 37 | 37 | 15 | 11 | 3.79 | .320 | 1.35 | 7.7 | 4.5 | 7.5 | 230.1 | 197 | 112 | 97 | 30 | 115 | 192 | 0 | 0 | 0 | 0 | 21 | 13 | 1 | 4.70 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 35 | 35 | 19 | 10 | 4.73 | .319 | 1.38 | 8.6 | 3.8 | 5.6 | 230.0 | 220 | 134 | 121 | 28 | 98 | 143 | 1 | 0 | 0 | 0 | 17 | 5 | 5 | 4.68 |
| SP | Carlton, S.Carlton, Steve # >> | 28 | 1972 | L | 51 | 35 | 35 | 16 | 12 | 5.41 | .334 | 1.47 | 9.2 | 4.0 | 5.3 | 236.1 | 241 | 154 | 142 | 34 | 106 | 140 | 4 | 0 | 0 | 1 | 14 | 8 | 3 | 5.14 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 92 | 0 | 2 | 2 | 3.19 | .314 | 1.34 | 7.5 | 4.5 | 8.1 | 62.0 | 52 | 24 | 22 | 6 | 31 | 56 | 0 | 2 | 0 | 0 | 0 | 2 | 5 | 4.05 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 34 | 84 | 0 | 3 | 1 | 4.19 | .270 | 1.08 | 7.1 | 2.7 | 6.7 | 66.2 | 52 | 35 | 31 | 7 | 20 | 49 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.89 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 61 | 0 | 5 | 4 | 4.50 | .330 | 1.43 | 9.0 | 3.9 | 10.0 | 46.0 | 46 | 25 | 23 | 5 | 20 | 51 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.63 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 76 | 0 | 1 | 1 | 5.33 | .311 | 1.35 | 8.7 | 3.5 | 7.0 | 54.0 | 52 | 35 | 32 | 11 | 21 | 42 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.26 |
| SU | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 62 | 0 | 4 | 3 | 2.83 | .254 | 1.01 | 6.3 | 2.9 | 9.7 | 63.2 | 44 | 21 | 20 | 10 | 20 | 68 | 0 | 5 | 5 | 0 | 0 | 1 | 1 | 3.90 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 35 | 33 | 7 | 20 | 6.01 | .326 | 1.42 | 10.1 | 2.7 | 8.0 | 220.0 | 246 | 158 | 147 | 31 | 66 | 196 | 5 | 0 | 0 | 1 | 12 | 7 | 4 | 4.05 |
| CL | Percival, T.Percival, Troy † >> | 26 | 1995 | R | 83 | 62 | 0 | 0 | 1 | 4.01 | .319 | 1.37 | 7.3 | 5.1 | 8.5 | 58.1 | 47 | 28 | 26 | 9 | 33 | 55 | 0 | 46 | 6 | 0 | 0 | 2 | 1 | 4.93 |