| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 83 | 20 | 20 | 11 | 3 | 2.63 | .254 | 1.01 | 6.9 | 2.1 | 5.4 | 147.0 | 113 | 44 | 43 | 14 | 35 | 88 | 4 | 0 | 0 | 1 | 15 | 2 | 2 | 3.80 |
| SP | Snell, B.Snell, Blake † # >> | 25 | 2018 | L | 81 | 19 | 19 | 10 | 2 | 2.73 | .252 | 0.97 | 5.8 | 2.9 | 8.9 | 122.0 | 79 | 41 | 37 | 9 | 39 | 121 | 1 | 0 | 0 | 1 | 12 | 5 | 5 | 3.06 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 19 | 19 | 7 | 7 | 3.68 | .321 | 1.35 | 7.0 | 5.2 | 7.9 | 110.0 | 86 | 46 | 45 | 11 | 63 | 97 | 0 | 0 | 0 | 0 | 7 | 7 | 0 | 4.45 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 46 | 19 | 19 | 7 | 9 | 5.99 | .363 | 1.70 | 9.4 | 5.9 | 8.2 | 106.2 | 111 | 74 | 71 | 16 | 70 | 96 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 5.16 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 54 | 0 | 3 | 1 | 3.59 | .311 | 1.31 | 7.8 | 4.1 | 9.0 | 62.2 | 54 | 26 | 25 | 5 | 28 | 62 | 0 | 1 | 2 | 0 | 0 | 3 | 2 | 3.55 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 27 | 0 | 2 | 0 | 1.91 | .241 | 0.95 | 3.5 | 5.1 | 8.0 | 28.1 | 11 | 6 | 6 | 1 | 16 | 25 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 3.39 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 28 | 0 | 0 | 1 | 3.49 | .288 | 1.19 | 7.6 | 3.3 | 10.4 | 38.2 | 32 | 15 | 15 | 2 | 14 | 44 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.55 |