| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 21 | 21 | 5 | 7 | 4.26 | .302 | 1.28 | 8.5 | 3.0 | 8.7 | 116.1 | 110 | 57 | 55 | 13 | 39 | 112 | 0 | 0 | 0 | 0 | 10 | 2 | 0 | 3.59 |
| SP | Johnson, W.Johnson, Walter # >> | 26 | 1913 | R | 95 | 20 | 20 | 5 | 11 | 4.44 | .286 | 1.17 | 8.7 | 1.9 | 4.7 | 135.2 | 131 | 73 | 67 | 14 | 28 | 71 | 4 | 0 | 0 | 0 | 9 | 4 | 1 | 4.01 |
| SP | Hubbell, C.Hubbell, Carl >> | 30 | 1933 | L | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 7 | 7 | 1 | 3 | 5.62 | .294 | 1.25 | 8.8 | 2.6 | 5.3 | 41.2 | 40 | 28 | 26 | 9 | 12 | 24 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 5.56 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 46 | 0 | 6 | 2 | 3.65 | .309 | 1.31 | 7.5 | 4.3 | 6.2 | 86.1 | 72 | 37 | 35 | 6 | 41 | 59 | 0 | 5 | 1 | 0 | 0 | 3 | 1 | 4.07 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 30 | 1983 | R | 28 | 27 | 0 | 1 | 2 | 3.35 | .249 | 0.99 | 8.6 | 0.4 | 4.9 | 48.1 | 46 | 19 | 18 | 10 | 2 | 26 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 51 | 0 | 5 | 1 | 3.90 | .310 | 1.35 | 7.7 | 4.5 | 8.7 | 60.0 | 51 | 31 | 26 | 8 | 30 | 58 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.30 |
| RP | Gagne, E.Gagne, Eric # >> | 27 | 2003 | R | 98 | 24 | 0 | 1 | 3 | 5.72 | .341 | 1.55 | 9.0 | 5.1 | 8.7 | 28.1 | 28 | 18 | 18 | 5 | 16 | 27 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 5.11 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 1 | 54.00 | .714 | 7.50 | - | - | - | 0.2 | 3 | 4 | 4 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |