| SP | Martinez, P.Martinez, Pedro $$ >> | 29 | 2000 | R | 100 | 12 | 12 | 3 | 5 | 4.22 | .315 | 1.32 | 8.5 | 3.3 | 9.9 | 79.0 | 75 | 37 | 37 | 14 | 29 | 87 | 1 | 0 | 0 | 1 | 6 | 5 | 0 | 4.39 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 11 | 11 | 3 | 4 | 4.52 | .303 | 1.29 | 7.4 | 4.3 | 9.1 | 73.2 | 60 | 38 | 37 | 8 | 35 | 74 | 1 | 0 | 0 | 0 | 6 | 1 | 2 | 3.88 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 81 | 12 | 12 | 6 | 4 | 4.02 | .299 | 1.20 | 8.0 | 2.8 | 8.5 | 85.0 | 76 | 38 | 38 | 13 | 26 | 80 | 3 | 0 | 0 | 0 | 8 | 7 | 1 | 4.27 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 11 | 11 | 4 | 6 | 5.14 | .325 | 1.41 | 9.6 | 3.1 | 6.3 | 63.0 | 67 | 40 | 36 | 12 | 22 | 44 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 5.22 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 29 | 0 | 1 | 4 | 4.60 | .273 | 1.09 | 7.4 | 2.5 | 10.2 | 29.1 | 24 | 15 | 15 | 4 | 8 | 33 | 0 | 13 | 3 | 0 | 0 | 1 | 0 | 3.45 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 86 | 37 | 0 | 0 | 0 | 3.64 | .282 | 1.18 | 7.8 | 3.1 | 10.9 | 29.2 | 25 | 12 | 12 | 4 | 10 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.41 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 35 | 0 | 3 | 2 | 3.90 | .268 | 1.07 | 8.1 | 1.5 | 9.6 | 30.0 | 27 | 16 | 13 | 6 | 5 | 32 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.07 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 30 | 0 | 0 | 0 | 2.10 | .217 | 0.80 | 3.9 | 3.3 | 12.3 | 30.0 | 13 | 8 | 7 | 1 | 11 | 41 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.90 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 73 | 23 | 0 | 2 | 0 | 3.60 | .250 | 0.92 | 7.2 | 1.1 | 9.0 | 25.0 | 20 | 10 | 10 | 3 | 3 | 25 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.16 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 59 | 33 | 0 | 0 | 2 | 7.56 | .398 | 1.98 | 14.1 | 4.5 | 10.1 | 16.2 | 25 | 14 | 14 | 1 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.06 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 4 | 2 | 1 | 2 | 6.23 | .297 | 1.27 | 10.1 | 1.6 | 5.3 | 17.1 | 19 | 12 | 12 | 4 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.41 |