| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 24 | 24 | 10 | 12 | 3.86 | .283 | 1.18 | 8.2 | 2.4 | 9.2 | 170.0 | 155 | 76 | 73 | 27 | 46 | 174 | 4 | 0 | 0 | 0 | 14 | 0 | 5 | 3.83 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 24 | 24 | 5 | 12 | 6.13 | .325 | 1.42 | 9.3 | 3.5 | 6.1 | 148.1 | 153 | 104 | 101 | 32 | 57 | 100 | 2 | 0 | 0 | 1 | 7 | 4 | 6 | 5.70 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 23 | 23 | 7 | 11 | 5.55 | .327 | 1.39 | 9.2 | 3.4 | 7.7 | 136.1 | 139 | 89 | 84 | 25 | 51 | 116 | 1 | 0 | 0 | 0 | 9 | 9 | 4 | 5.01 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 59 | 23 | 23 | 10 | 10 | 5.49 | .330 | 1.46 | 10.2 | 3.0 | 10.1 | 142.2 | 161 | 92 | 87 | 31 | 48 | 160 | 2 | 0 | 0 | 1 | 11 | 2 | 3 | 4.64 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 23 | 22 | 3 | 9 | 4.22 | .310 | 1.34 | 8.3 | 3.9 | 6.2 | 121.2 | 111 | 60 | 57 | 18 | 52 | 83 | 0 | 1 | 0 | 0 | 9 | 1 | 0 | 4.88 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 42 | 0 | 0 | 2 | 7.17 | .372 | 1.65 | 10.9 | 4.1 | 10.9 | 37.2 | 45 | 34 | 30 | 9 | 17 | 45 | 0 | 1 | 6 | 0 | 0 | 5 | 1 | 5.51 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 42 | 0 | 3 | 0 | 5.12 | .329 | 1.47 | 9.7 | 3.8 | 12.6 | 38.2 | 41 | 22 | 22 | 6 | 16 | 53 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.53 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 28 | 0 | 2 | 1 | 4.33 | .319 | 1.41 | 9.3 | 3.3 | 9.3 | 27.0 | 28 | 14 | 13 | 6 | 10 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.93 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 26 | 0 | 0 | 1 | 3.49 | .336 | 1.48 | 6.4 | 7.1 | 12.2 | 28.1 | 20 | 12 | 11 | 2 | 22 | 38 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3.68 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 57 | 20 | 0 | 1 | 1 | 7.62 | .410 | 2.05 | 11.3 | 7.3 | 10.6 | 69.2 | 87 | 59 | 59 | 12 | 56 | 81 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5.43 |