| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 90 | 36 | 36 | 19 | 13 | 3.61 | .263 | 1.03 | 7.6 | 1.7 | 5.7 | 261.2 | 219 | 114 | 105 | 29 | 50 | 165 | 9 | 0 | 0 | 3 | 22 | 11 | 7 | 3.88 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 93 | 35 | 35 | 13 | 9 | 3.66 | .304 | 1.27 | 6.9 | 4.5 | 9.2 | 241.0 | 184 | 107 | 98 | 25 | 121 | 246 | 0 | 0 | 0 | 0 | 23 | 11 | 5 | 3.95 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 74 | 0 | 5 | 5 | 2.86 | .258 | 1.00 | 5.9 | 3.2 | 8.6 | 100.2 | 65 | 32 | 32 | 10 | 36 | 96 | 0 | 3 | 6 | 0 | 0 | 4 | 0 | 3.58 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 57 | 0 | 4 | 4 | 3.08 | .303 | 1.29 | 8.1 | 3.5 | 6.9 | 61.1 | 55 | 24 | 21 | 3 | 24 | 47 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.33 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 26 | 0 | 1 | 0 | 2.14 | .257 | 1.01 | 4.9 | 4.4 | 8.2 | 33.2 | 18 | 8 | 8 | 2 | 16 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 22 | 0 | 1 | 1 | 4.08 | .317 | 1.40 | 8.4 | 4.5 | 9.0 | 28.2 | 26 | 13 | 13 | 4 | 14 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.36 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 72 | 0 | 2 | 5 | 3.44 | .284 | 1.18 | 7.1 | 3.4 | 9.9 | 68.0 | 54 | 26 | 26 | 9 | 26 | 75 | 0 | 50 | 4 | 0 | 0 | 1 | 4 | 3.71 |
| SP | Perry, G.Perry, Gaylord # >> | 34 | 1972 | R | 69 | 29 | 29 | 15 | 13 | 3.89 | .282 | 1.16 | 7.9 | 2.5 | 5.4 | 208.1 | 183 | 99 | 90 | 24 | 58 | 125 | 9 | 0 | 0 | 2 | 16 | 5 | 5 | 4.21 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 57 | 24 | 0 | 3 | 5 | 3.93 | .302 | 1.27 | 7.9 | 3.6 | 9.1 | 91.2 | 80 | 41 | 40 | 13 | 36 | 92 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 4.12 |