| SP | Johnson, R.Johnson, Randy $ >> | 41 | 2004 | L | 90 | 24 | 24 | 7 | 11 | 3.60 | .286 | 1.16 | 8.0 | 2.5 | 9.0 | 162.2 | 144 | 67 | 65 | 14 | 45 | 162 | 2 | 0 | 0 | 0 | 15 | 6 | 4 | 3.07 |
| SP | Snell, B.Snell, Blake $$ >> | 25 | 2018 | L | 88 | 23 | 23 | 10 | 7 | 3.79 | .296 | 1.23 | 6.8 | 4.4 | 10.0 | 130.2 | 98 | 57 | 55 | 14 | 63 | 145 | 0 | 0 | 0 | 0 | 14 | 4 | 4 | 3.72 |
| SP | Perry, G.Perry, Gaylord # >> | 34 | 1972 | R | 69 | 23 | 23 | 6 | 9 | 4.44 | .301 | 1.26 | 8.1 | 3.3 | 5.8 | 148.0 | 133 | 78 | 73 | 18 | 54 | 95 | 3 | 0 | 0 | 1 | 11 | 4 | 5 | 4.47 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 67 | 23 | 23 | 8 | 9 | 5.71 | .327 | 1.42 | 8.9 | 3.9 | 9.4 | 121.1 | 119 | 79 | 77 | 13 | 53 | 127 | 0 | 0 | 0 | 0 | 9 | 5 | 2 | 3.74 |
| CL | Wagner, B.Wagner, Billy † $ >> | 28 | 1999 | L | 93 | 52 | 0 | 3 | 4 | 2.94 | .307 | 1.31 | 8.1 | 3.7 | 9.2 | 49.0 | 44 | 18 | 16 | 5 | 20 | 50 | 0 | 30 | 4 | 0 | 0 | 1 | 0 | 3.57 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 42 | 0 | 1 | 3 | 3.53 | .297 | 1.27 | 8.6 | 2.9 | 9.6 | 43.1 | 41 | 18 | 17 | 4 | 14 | 46 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 3.05 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 67 | 0 | 5 | 1 | 5.07 | .328 | 1.41 | 9.9 | 2.8 | 9.5 | 71.0 | 78 | 44 | 40 | 12 | 22 | 75 | 0 | 2 | 1 | 0 | 0 | 4 | 3 | 4.18 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 45 | 0 | 3 | 3 | 5.62 | .371 | 1.75 | 10.3 | 5.7 | 9.7 | 49.2 | 56 | 36 | 31 | 11 | 31 | 53 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.71 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 73 | 33 | 0 | 1 | 1 | 4.60 | .328 | 1.47 | 9.6 | 3.7 | 9.9 | 29.1 | 31 | 16 | 15 | 4 | 12 | 32 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 3.83 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 19 | 0 | 4 | 2 | 6.25 | .333 | 1.46 | 10.1 | 3.0 | 8.1 | 72.0 | 81 | 50 | 50 | 19 | 24 | 65 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 5.75 |