| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 12 | 12 | 3 | 7 | 6.26 | .337 | 1.51 | 11.6 | 2.1 | 8.9 | 73.1 | 94 | 56 | 51 | 12 | 17 | 72 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 3.90 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 12 | 12 | 3 | 3 | 4.04 | .343 | 1.54 | 9.0 | 4.8 | 9.7 | 69.0 | 69 | 32 | 31 | 5 | 37 | 74 | 0 | 0 | 0 | 0 | 6 | 2 | 3 | 3.49 |
| SP | Flaherty, J.Flaherty, Jack # >> | 23 | 2019 | R | 83 | 12 | 12 | 1 | 4 | 5.21 | .309 | 1.29 | 9.1 | 2.5 | 8.8 | 76.0 | 77 | 45 | 44 | 15 | 21 | 74 | 0 | 0 | 0 | 0 | 5 | 4 | 3 | 4.61 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 11 | 11 | 6 | 2 | 5.42 | .332 | 1.47 | 10.3 | 3.1 | 7.1 | 79.2 | 90 | 48 | 48 | 11 | 27 | 62 | 3 | 0 | 0 | 1 | 3 | 2 | 2 | 4.34 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 11 | 11 | 5 | 3 | 5.06 | .319 | 1.38 | 9.0 | 3.5 | 7.8 | 74.2 | 74 | 44 | 42 | 12 | 29 | 64 | 2 | 0 | 0 | 2 | 6 | 2 | 1 | 4.64 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 39 | 0 | 5 | 0 | 4.30 | .254 | 0.98 | 7.2 | 1.6 | 10.4 | 44.0 | 35 | 21 | 21 | 5 | 8 | 51 | 0 | 4 | 0 | 0 | 0 | 2 | 2 | 2.84 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 32 | 0 | 4 | 1 | 2.37 | .272 | 1.05 | 6.6 | 3.0 | 10.5 | 30.1 | 22 | 9 | 8 | 4 | 10 | 35 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 15 | 0 | 2 | 3 | 3.38 | .273 | 1.13 | 9.6 | 0.6 | 8.4 | 16.0 | 17 | 7 | 6 | 2 | 1 | 15 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.94 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 5 | 0 | 0 | 0 | 0.00 | .176 | 0.64 | 4.5 | 2.3 | 4.5 | 4.2 | 2 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.75 |