| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 27 | 27 | 11 | 10 | 3.49 | .285 | 1.18 | 7.9 | 2.8 | 8.4 | 198.2 | 173 | 81 | 77 | 22 | 61 | 184 | 5 | 0 | 0 | 0 | 16 | 3 | 5 | 3.56 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 26 | 26 | 5 | 13 | 5.51 | .355 | 1.62 | 9.6 | 5.0 | 7.8 | 145.1 | 155 | 92 | 89 | 22 | 81 | 126 | 2 | 0 | 0 | 0 | 11 | 4 | 3 | 4.99 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 75 | 0 | 3 | 5 | 3.58 | .278 | 1.11 | 7.8 | 2.2 | 9.1 | 98.0 | 85 | 41 | 39 | 12 | 24 | 99 | 0 | 1 | 1 | 0 | 0 | 4 | 4 | 3.43 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 92 | 58 | 0 | 3 | 10 | 3.65 | .276 | 1.12 | 6.8 | 3.3 | 9.4 | 69.0 | 52 | 31 | 28 | 8 | 25 | 72 | 0 | 23 | 1 | 0 | 0 | 2 | 0 | 3.59 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 55 | 0 | 4 | 2 | 4.10 | .323 | 1.41 | 9.6 | 3.3 | 9.0 | 63.2 | 67 | 30 | 29 | 4 | 23 | 63 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 2.97 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 41 | 0 | 3 | 1 | 3.65 | .298 | 1.25 | 7.9 | 3.5 | 7.6 | 56.2 | 49 | 24 | 23 | 6 | 22 | 47 | 0 | 2 | 0 | 0 | 0 | 1 | 6 | 3.95 |