| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 34 | 34 | 8 | 16 | 4.62 | .307 | 1.32 | 9.3 | 2.6 | 5.7 | 234.0 | 241 | 132 | 120 | 27 | 68 | 148 | 6 | 0 | 0 | 2 | 16 | 2 | 2 | 4.13 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 32 | 32 | 8 | 12 | 5.99 | .338 | 1.52 | 10.8 | 2.9 | 5.4 | 198.1 | 238 | 140 | 132 | 30 | 64 | 119 | 2 | 0 | 0 | 1 | 11 | 2 | 5 | 4.77 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 31 | 31 | 2 | 6 | 5.28 | .312 | 1.34 | 8.6 | 3.6 | 9.6 | 134.2 | 128 | 83 | 79 | 30 | 53 | 143 | 0 | 0 | 0 | 0 | 2 | 2 | 4 | 5.01 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 84 | 0 | 15 | 4 | 3.26 | .294 | 1.23 | 7.2 | 3.9 | 8.9 | 135.1 | 108 | 59 | 49 | 11 | 59 | 133 | 0 | 7 | 9 | 0 | 0 | 2 | 0 | 3.44 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 78 | 0 | 5 | 7 | 4.44 | .327 | 1.44 | 8.4 | 4.5 | 5.8 | 95.1 | 89 | 48 | 47 | 12 | 48 | 61 | 0 | 9 | 3 | 0 | 0 | 2 | 0 | 4.94 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 64 | 0 | 6 | 5 | 6.17 | .327 | 1.42 | 7.6 | 5.3 | 4.7 | 81.2 | 68 | 66 | 56 | 10 | 48 | 42 | 0 | 5 | 3 | 0 | 0 | 3 | 2 | 5.46 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 49 | 0 | 1 | 7 | 4.53 | .333 | 1.49 | 8.6 | 4.8 | 6.8 | 101.1 | 97 | 51 | 51 | 6 | 54 | 76 | 0 | 4 | 3 | 0 | 0 | 1 | 3 | 3.90 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 4 | 0 | 0 | 0 | 9.00 | .444 | 2.40 | 9.0 | 12.6 | 5.4 | 5.0 | 5 | 5 | 5 | 1 | 7 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.60 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 42 | 0 | 5 | 5 | 6.13 | .378 | 1.78 | 11.9 | 4.1 | 6.3 | 72.0 | 95 | 49 | 49 | 8 | 33 | 50 | 0 | 3 | 2 | 0 | 0 | 3 | 2 | 4.56 |