| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 27 | 27 | 5 | 13 | 4.13 | .311 | 1.34 | 9.0 | 3.1 | 4.8 | 196.1 | 196 | 94 | 90 | 20 | 67 | 105 | 3 | 0 | 0 | 0 | 17 | 3 | 4 | 4.33 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 26 | 26 | 14 | 9 | 3.53 | .284 | 1.16 | 9.1 | 1.3 | 5.1 | 196.1 | 199 | 89 | 77 | 18 | 29 | 110 | 2 | 0 | 0 | 1 | 16 | 6 | 3 | 3.61 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 25 | 25 | 12 | 10 | 3.98 | .297 | 1.25 | 8.2 | 3.1 | 5.4 | 183.0 | 166 | 86 | 81 | 20 | 63 | 110 | 7 | 0 | 0 | 1 | 12 | 3 | 2 | 4.30 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 75 | 0 | 2 | 3 | 3.53 | .302 | 1.28 | 7.3 | 4.2 | 8.2 | 97.0 | 79 | 41 | 38 | 4 | 45 | 88 | 0 | 11 | 3 | 0 | 0 | 2 | 3 | 3.18 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 65 | 0 | 6 | 3 | 3.08 | .288 | 1.20 | 5.8 | 5.0 | 8.8 | 79.0 | 51 | 30 | 27 | 5 | 44 | 77 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 3.58 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 47 | 0 | 3 | 2 | 1.98 | .296 | 1.26 | 8.3 | 3.2 | 6.0 | 54.2 | 50 | 17 | 12 | 6 | 19 | 36 | 0 | 6 | 2 | 0 | 0 | 0 | 4 | 4.17 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 15 | 0 | 2 | 1 | 3.55 | .303 | 1.30 | 8.6 | 3.2 | 4.3 | 25.1 | 24 | 10 | 10 | 4 | 9 | 12 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.20 |