| SP | deGrom, J.deGrom, Jacob † # >> | 33 | 2021 | R | 100 | 35 | 35 | 20 | 11 | 3.02 | .250 | 0.98 | 7.0 | 1.9 | 9.8 | 238.1 | 184 | 87 | 80 | 23 | 50 | 259 | 2 | 0 | 0 | 2 | 24 | 4 | 0 | 2.76 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 34 | 33 | 10 | 13 | 5.12 | .343 | 1.55 | 9.2 | 4.8 | 8.7 | 188.0 | 192 | 122 | 107 | 32 | 100 | 181 | 0 | 0 | 0 | 0 | 13 | 2 | 3 | 4.91 |
| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 60 | 35 | 31 | 11 | 11 | 5.20 | .339 | 1.52 | 9.5 | 4.3 | 5.6 | 209.1 | 220 | 129 | 121 | 25 | 99 | 131 | 2 | 0 | 0 | 0 | 13 | 3 | 3 | 4.77 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 66 | 0 | 2 | 0 | 1.91 | .293 | 1.23 | 6.0 | 5.1 | 8.2 | 70.2 | 47 | 18 | 15 | 4 | 40 | 64 | 0 | 35 | 4 | 0 | 0 | 1 | 1 | 3.67 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 56 | 0 | 1 | 2 | 5.07 | .335 | 1.47 | 8.5 | 4.7 | 9.5 | 55.0 | 52 | 31 | 31 | 7 | 29 | 58 | 0 | 2 | 3 | 0 | 0 | 2 | 3 | 4.24 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 57 | 0 | 3 | 0 | 4.32 | .319 | 1.37 | 6.7 | 5.7 | 9.5 | 58.1 | 43 | 31 | 28 | 5 | 37 | 61 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.03 |