| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 11 | 11 | 4 | 3 | 5.25 | .290 | 1.22 | 9.3 | 1.8 | 10.8 | 70.1 | 72 | 43 | 41 | 10 | 14 | 84 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 3.06 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 11 | 11 | 6 | 5 | 5.30 | .313 | 1.36 | 9.5 | 2.7 | 4.6 | 73.0 | 77 | 43 | 43 | 15 | 22 | 37 | 2 | 0 | 0 | 0 | 4 | 1 | 1 | 5.60 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 10 | 10 | 3 | 4 | 6.00 | .377 | 1.78 | 10.8 | 5.2 | 3.3 | 54.0 | 65 | 38 | 36 | 8 | 31 | 20 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 6.02 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 10 | 10 | 3 | 2 | 4.04 | .327 | 1.46 | 9.1 | 4.1 | 2.8 | 62.1 | 63 | 29 | 28 | 8 | 28 | 19 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 5.42 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 31 | 0 | 4 | 1 | 3.89 | .298 | 1.25 | 8.8 | 2.6 | 9.4 | 41.2 | 40 | 18 | 18 | 5 | 12 | 43 | 0 | 4 | 3 | 0 | 0 | 1 | 1 | 3.44 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 21 | 0 | 2 | 3 | 6.85 | .362 | 1.70 | 11.5 | 4.1 | 10.6 | 22.1 | 28 | 18 | 17 | 5 | 10 | 26 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.95 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 12 | 0 | 0 | 1 | 6.05 | .389 | 1.86 | 12.8 | 4.3 | 6.2 | 19.1 | 27 | 13 | 13 | 2 | 9 | 13 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.58 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 4 | 0 | 1 | 0 | 0.00 | .296 | 1.26 | 4.5 | 7.5 | 6.0 | 6.1 | 3 | 0 | 0 | 0 | 5 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.17 |