| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 19 | 19 | 7 | 8 | 4.74 | .308 | 1.29 | 8.5 | 3.1 | 7.1 | 129.0 | 122 | 69 | 68 | 21 | 44 | 102 | 1 | 0 | 0 | 1 | 8 | 6 | 2 | 4.70 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 86 | 18 | 18 | 7 | 6 | 3.58 | .299 | 1.24 | 8.3 | 2.9 | 7.9 | 123.1 | 113 | 56 | 49 | 15 | 40 | 108 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 3.93 |
| SP | Santana, E.Santana, Ervin # >> | 25 | 2008 | R | 55 | 17 | 17 | 5 | 8 | 4.65 | .323 | 1.42 | 10.6 | 2.2 | 8.1 | 110.1 | 130 | 58 | 57 | 23 | 27 | 99 | 1 | 0 | 0 | 0 | 6 | 1 | 2 | 4.68 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 54 | 17 | 17 | 4 | 7 | 5.64 | .344 | 1.56 | 11.8 | 2.2 | 7.2 | 99.0 | 130 | 62 | 62 | 16 | 24 | 79 | 0 | 0 | 0 | 0 | 8 | 2 | 8 | 4.29 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 47 | 0 | 2 | 6 | 7.16 | .364 | 1.68 | 11.8 | 3.4 | 8.2 | 55.1 | 72 | 46 | 44 | 16 | 21 | 50 | 0 | 4 | 4 | 0 | 0 | 2 | 0 | 6.22 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 42 | 0 | 1 | 1 | 4.73 | .300 | 1.27 | 9.5 | 1.9 | 9.2 | 51.1 | 54 | 32 | 27 | 12 | 11 | 52 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Donnelly, B.Donnelly, Brendan >> | 32 | 2003 | R | 39 | 24 | 0 | 0 | 1 | 5.22 | .380 | 1.77 | 9.3 | 6.8 | 9.3 | 29.1 | 30 | 18 | 17 | 3 | 22 | 30 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.76 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 47 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Mulder, M.Mulder, Mark >> | 24 | 2001 | L | 29 | 20 | 0 | 5 | 0 | 2.63 | .281 | 1.10 | 7.3 | 2.7 | 5.0 | 27.1 | 22 | 8 | 8 | 4 | 8 | 15 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.93 |