| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 20 | 20 | 7 | 8 | 3.86 | .300 | 1.25 | 8.6 | 2.7 | 9.8 | 128.1 | 122 | 55 | 55 | 17 | 39 | 139 | 1 | 0 | 0 | 0 | 12 | 4 | 2 | 3.56 |
| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 89 | 18 | 18 | 8 | 6 | 3.69 | .279 | 1.16 | 7.8 | 2.6 | 8.8 | 124.1 | 108 | 56 | 51 | 17 | 36 | 121 | 2 | 0 | 0 | 2 | 9 | 0 | 3 | 3.70 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 81 | 18 | 18 | 7 | 8 | 5.69 | .337 | 1.49 | 10.5 | 2.9 | 8.4 | 104.1 | 121 | 68 | 66 | 19 | 34 | 97 | 0 | 0 | 0 | 0 | 4 | 4 | 1 | 4.61 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 48 | 0 | 4 | 2 | 5.15 | .300 | 1.28 | 10.1 | 1.5 | 9.3 | 64.2 | 72 | 39 | 37 | 9 | 11 | 66 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 86 | 44 | 0 | 4 | 0 | 1.05 | .241 | 0.94 | 4.8 | 3.7 | 10.2 | 51.1 | 27 | 6 | 6 | 2 | 21 | 58 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 2.53 |
| RP | Gordon, T.Gordon, Tom † >> | 37 | 2004 | R | 81 | 37 | 0 | 7 | 0 | 0.86 | .217 | 0.81 | 6.0 | 1.3 | 8.1 | 42.0 | 28 | 6 | 4 | 1 | 6 | 38 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 2.00 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 16 | 0 | 0 | 0 | 2.37 | .269 | 1.11 | 8.5 | 1.4 | 7.1 | 19.0 | 18 | 7 | 5 | 2 | 3 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.26 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 15 | 0 | 1 | 2 | 2.04 | .243 | 0.96 | 5.3 | 3.7 | 7.4 | 17.2 | 10 | 4 | 4 | 1 | 7 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.35 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 17 | 0 | 0 | 1 | 3.00 | .325 | 1.44 | 6.5 | 6.5 | 11.5 | 18.0 | 13 | 6 | 6 | 3 | 13 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.78 |
| CL | Gagne, E.Gagne, Eric † $ >> | 27 | 2003 | R | 100 | 38 | 0 | 3 | 2 | 1.75 | .289 | 1.22 | 6.8 | 4.3 | 10.5 | 36.0 | 27 | 7 | 7 | 1 | 17 | 42 | 0 | 27 | 0 | 0 | 0 | 0 | 0 | 2.44 |