| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 97 | 36 | 36 | 14 | 14 | 4.08 | .307 | 1.29 | 8.2 | 3.4 | 9.0 | 258.1 | 235 | 128 | 117 | 40 | 98 | 258 | 2 | 0 | 0 | 0 | 18 | 10 | 3 | 4.27 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 84 | 34 | 34 | 8 | 17 | 4.64 | .315 | 1.35 | 9.5 | 2.7 | 6.8 | 236.2 | 250 | 144 | 122 | 46 | 70 | 177 | 6 | 0 | 0 | 1 | 17 | 7 | 6 | 5.01 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 64 | 27 | 22 | 10 | 8 | 5.35 | .358 | 1.64 | 10.4 | 4.4 | 8.4 | 149.2 | 173 | 101 | 89 | 23 | 73 | 139 | 0 | 1 | 0 | 0 | 9 | 4 | 5 | 4.69 |
| SP | Gallen, Z.Gallen, Zac # >> | 26 | 2022 | R | 92 | 31 | 29 | 10 | 11 | 4.61 | .304 | 1.28 | 8.9 | 2.7 | 7.4 | 183.2 | 181 | 101 | 94 | 25 | 54 | 150 | 1 | 0 | 0 | 1 | 15 | 6 | 2 | 4.12 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 86 | 0 | 6 | 2 | 4.91 | .345 | 1.57 | 10.4 | 3.8 | 10.6 | 84.1 | 97 | 52 | 46 | 17 | 35 | 99 | 0 | 0 | 3 | 0 | 0 | 1 | 3 | 4.56 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 64 | 71 | 0 | 4 | 0 | 3.44 | .279 | 1.11 | 6.2 | 3.9 | 7.2 | 83.2 | 57 | 35 | 32 | 10 | 36 | 66 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 4.42 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 48 | 0 | 2 | 1 | 2.72 | .284 | 1.14 | 6.1 | 4.2 | 9.8 | 56.1 | 38 | 17 | 17 | 4 | 26 | 61 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 3.30 |