| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 10 | 18 | 3.86 | .310 | 1.31 | 8.8 | 3.0 | 10.7 | 217.0 | 211 | 98 | 93 | 32 | 73 | 258 | 1 | 0 | 0 | 0 | 18 | 8 | 0 | 3.66 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 33 | 33 | 7 | 19 | 5.72 | .338 | 1.51 | 9.9 | 3.7 | 8.6 | 187.1 | 206 | 126 | 119 | 37 | 76 | 178 | 0 | 0 | 0 | 0 | 12 | 5 | 8 | 4.97 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 32 | 32 | 4 | 16 | 5.97 | .345 | 1.55 | 9.8 | 4.1 | 9.6 | 187.0 | 204 | 128 | 124 | 36 | 85 | 200 | 0 | 0 | 0 | 0 | 9 | 7 | 7 | 4.84 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 72 | 32 | 32 | 13 | 15 | 5.66 | .324 | 1.42 | 9.7 | 3.1 | 6.3 | 227.1 | 245 | 146 | 143 | 42 | 78 | 159 | 10 | 0 | 0 | 1 | 12 | 4 | 6 | 5.09 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 68 | 0 | 1 | 3 | 2.61 | .269 | 1.09 | 5.5 | 4.3 | 10.0 | 69.0 | 42 | 23 | 20 | 5 | 33 | 77 | 0 | 34 | 5 | 0 | 0 | 1 | 1 | 3.19 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 83 | 0 | 4 | 4 | 4.24 | .276 | 1.14 | 6.6 | 3.7 | 9.3 | 108.1 | 79 | 54 | 51 | 16 | 44 | 112 | 0 | 0 | 3 | 0 | 0 | 1 | 3 | 4.10 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 82 | 0 | 6 | 2 | 3.00 | .289 | 1.22 | 7.9 | 3.1 | 8.1 | 99.0 | 87 | 35 | 33 | 9 | 34 | 89 | 0 | 0 | 1 | 0 | 0 | 0 | 8 | 3.41 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 79 | 56 | 0 | 1 | 3 | 4.79 | .314 | 1.37 | 7.7 | 4.6 | 7.4 | 62.0 | 53 | 34 | 33 | 7 | 32 | 51 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.37 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 48 | 0 | 2 | 4 | 4.14 | .351 | 1.62 | 8.8 | 6.0 | 6.6 | 45.2 | 44 | 24 | 21 | 6 | 30 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.27 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 11 | 0 | 1 | 4 | 7.31 | .333 | 1.44 | 12.4 | 0.6 | 5.1 | 16.0 | 22 | 13 | 13 | 5 | 1 | 9 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.31 |