| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 97 | 30 | 30 | 10 | 12 | 4.41 | .298 | 1.28 | 7.7 | 3.9 | 10.5 | 175.2 | 149 | 90 | 86 | 29 | 75 | 205 | 1 | 0 | 0 | 0 | 15 | 0 | 4 | 4.10 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 29 | 29 | 9 | 10 | 4.26 | .332 | 1.48 | 8.3 | 5.1 | 8.6 | 164.2 | 151 | 83 | 78 | 16 | 93 | 156 | 0 | 0 | 0 | 0 | 13 | 2 | 3 | 4.10 |
| SP | Higuera, T.Higuera, Teddy # >> | 30 | 1988 | L | 64 | 29 | 29 | 4 | 10 | 5.00 | .343 | 1.56 | 10.7 | 3.4 | 6.3 | 174.2 | 207 | 104 | 97 | 26 | 65 | 122 | 3 | 0 | 0 | 0 | 12 | 1 | 0 | 4.68 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 59 | 29 | 29 | 10 | 12 | 4.53 | .334 | 1.48 | 8.8 | 4.6 | 7.3 | 196.2 | 191 | 102 | 99 | 26 | 100 | 160 | 2 | 0 | 0 | 0 | 14 | 5 | 2 | 4.70 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 79 | 0 | 6 | 5 | 3.71 | .311 | 1.33 | 7.5 | 4.5 | 9.1 | 111.2 | 93 | 50 | 46 | 10 | 56 | 112 | 0 | 7 | 5 | 0 | 0 | 2 | 4 | 3.72 |
| RP | Jackson, M.Jackson, Mike † >> | 30 | 1994 | R | 82 | 79 | 0 | 9 | 4 | 2.84 | .283 | 1.17 | 7.5 | 3.1 | 9.8 | 101.1 | 84 | 32 | 32 | 10 | 35 | 110 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 3.18 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 66 | 63 | 0 | 3 | 4 | 3.87 | .322 | 1.34 | 7.6 | 4.6 | 8.1 | 76.2 | 64 | 33 | 33 | 10 | 39 | 68 | 0 | 6 | 4 | 0 | 0 | 6 | 1 | 4.70 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 26 | 0 | 4 | 1 | 4.61 | .385 | 1.83 | 11.6 | 4.8 | 9.2 | 41.0 | 53 | 21 | 21 | 4 | 22 | 42 | 0 | 6 | 0 | 0 | 0 | 2 | 1 | 3.98 |