| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 6 | 6 | 3 | 0 | 2.98 | .282 | 1.13 | 8.4 | 1.9 | 3.4 | 42.1 | 39 | 18 | 14 | 3 | 9 | 16 | 1 | 0 | 0 | 0 | 5 | 2 | 0 | 3.95 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 5 | 5 | 4 | 0 | 3.11 | .252 | 0.98 | 7.1 | 1.9 | 5.1 | 37.2 | 29 | 13 | 13 | 4 | 8 | 21 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 4.00 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 5 | 5 | 3 | 2 | 3.45 | .329 | 1.44 | 9.6 | 3.5 | 7.3 | 31.1 | 33 | 12 | 12 | 4 | 12 | 25 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 4.32 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 5 | 5 | 1 | 2 | 9.78 | .431 | 2.12 | 16.6 | 2.8 | 3.3 | 19.1 | 35 | 21 | 21 | 2 | 6 | 7 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 5.05 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 12 | 0 | 1 | 0 | 3.14 | .295 | 1.19 | 8.4 | 2.6 | 10.9 | 14.1 | 13 | 7 | 5 | 2 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.50 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 11 | 0 | 1 | 1 | 2.03 | .259 | 0.98 | 3.5 | 5.5 | 5.5 | 13.1 | 5 | 3 | 3 | 0 | 8 | 8 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.85 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 9 | 0 | 0 | 0 | 3.27 | .267 | 1.09 | 9.8 | 0.0 | 9.0 | 11.0 | 12 | 4 | 4 | 1 | 0 | 11 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.18 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 5 | 0 | 0 | 0 | 4.05 | .333 | 1.50 | 10.5 | 4.5 | 10.5 | 6.2 | 7 | 3 | 3 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.17 |
| CL | Uehara, K.Uehara, Koji $ >> | 38 | 2013 | R | 100 | 14 | 0 | 1 | 2 | 2.11 | .256 | 1.03 | 7.3 | 2.1 | 8.1 | 21.1 | 17 | 7 | 5 | 0 | 5 | 19 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1.90 |