| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 13 | 12 | 4.05 | .288 | 1.19 | 8.4 | 2.3 | 8.5 | 209.0 | 195 | 111 | 94 | 32 | 53 | 197 | 0 | 0 | 0 | 0 | 21 | 5 | 0 | 3.94 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 11 | 10 | 4.84 | .321 | 1.40 | 9.6 | 3.0 | 7.8 | 210.0 | 223 | 119 | 113 | 34 | 71 | 183 | 3 | 0 | 0 | 1 | 13 | 4 | 3 | 4.43 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 31 | 31 | 11 | 11 | 5.09 | .326 | 1.43 | 10.7 | 2.2 | 4.7 | 200.0 | 238 | 127 | 113 | 24 | 48 | 104 | 4 | 0 | 0 | 0 | 15 | 4 | 3 | 4.30 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 70 | 0 | 5 | 5 | 3.40 | .270 | 1.08 | 7.2 | 2.6 | 10.0 | 79.1 | 63 | 32 | 30 | 12 | 23 | 88 | 0 | 15 | 5 | 0 | 0 | 2 | 0 | 3.70 |
| RP | Holland, G.Holland, Greg # >> | 27 | 2013 | R | 72 | 38 | 0 | 2 | 2 | 4.43 | .330 | 1.46 | 8.4 | 4.9 | 10.2 | 44.2 | 41 | 32 | 22 | 7 | 24 | 50 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 4.50 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 36 | 0 | 2 | 2 | 2.93 | .255 | 1.03 | 6.3 | 2.9 | 7.0 | 40.0 | 28 | 15 | 13 | 6 | 13 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.38 |