| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 24 | 24 | 14 | 5 | 2.98 | .282 | 1.16 | 6.3 | 4.1 | 7.7 | 196.0 | 138 | 68 | 65 | 13 | 90 | 168 | 6 | 0 | 0 | 3 | 16 | 3 | 5 | 3.57 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 23 | 23 | 8 | 7 | 4.94 | .309 | 1.31 | 9.9 | 1.9 | 7.6 | 140.1 | 154 | 80 | 77 | 19 | 30 | 118 | 2 | 0 | 0 | 0 | 13 | 4 | 12 | 3.81 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 22 | 22 | 7 | 10 | 4.53 | .322 | 1.40 | 9.4 | 3.2 | 4.3 | 165.0 | 172 | 87 | 83 | 22 | 59 | 79 | 6 | 0 | 0 | 0 | 10 | 4 | 3 | 4.92 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 64 | 22 | 22 | 6 | 8 | 6.16 | .360 | 1.66 | 10.6 | 4.4 | 4.9 | 122.2 | 144 | 87 | 84 | 21 | 60 | 66 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 5.70 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 58 | 0 | 4 | 5 | 3.27 | .291 | 1.20 | 7.4 | 3.5 | 9.0 | 82.2 | 67 | 31 | 30 | 6 | 32 | 82 | 0 | 4 | 4 | 0 | 0 | 3 | 1 | 3.23 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 56 | 0 | 1 | 5 | 4.41 | .307 | 1.29 | 7.5 | 4.2 | 8.7 | 65.1 | 54 | 32 | 32 | 10 | 30 | 63 | 0 | 8 | 0 | 0 | 0 | 3 | 3 | 4.58 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 42 | 0 | 4 | 5 | 4.29 | .314 | 1.37 | 8.1 | 4.3 | 8.6 | 50.1 | 45 | 24 | 24 | 7 | 24 | 48 | 0 | 5 | 2 | 0 | 0 | 0 | 3 | 4.34 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 27 | 0 | 4 | 1 | 4.40 | .294 | 1.25 | 8.4 | 2.9 | 5.8 | 59.1 | 55 | 29 | 29 | 7 | 19 | 38 | 0 | 4 | 0 | 0 | 0 | 0 | 6 | 4.22 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |