| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 23 | 23 | 9 | 10 | 4.09 | .289 | 1.18 | 8.5 | 2.2 | 8.0 | 158.1 | 149 | 76 | 72 | 22 | 38 | 140 | 1 | 0 | 0 | 1 | 12 | 6 | 1 | 3.87 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 23 | 23 | 7 | 10 | 4.59 | .311 | 1.33 | 9.1 | 2.9 | 4.9 | 168.2 | 170 | 95 | 86 | 21 | 55 | 92 | 3 | 0 | 0 | 2 | 9 | 3 | 4 | 4.57 |
| SP | Drysdale, D.Drysdale, Don # >> | 28 | 1964 | R | 59 | 21 | 21 | 7 | 10 | 5.19 | .330 | 1.43 | 9.6 | 3.2 | 5.4 | 154.1 | 165 | 100 | 89 | 25 | 55 | 92 | 8 | 0 | 0 | 0 | 9 | 8 | 3 | 5.14 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 59 | 0 | 7 | 2 | 2.42 | .272 | 1.09 | 6.7 | 3.1 | 8.2 | 89.1 | 66 | 25 | 24 | 8 | 31 | 81 | 0 | 7 | 4 | 0 | 0 | 3 | 0 | 3.49 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 43 | 0 | 2 | 6 | 3.78 | .299 | 1.28 | 9.7 | 1.9 | 8.7 | 52.1 | 56 | 22 | 22 | 4 | 11 | 50 | 0 | 7 | 0 | 0 | 0 | 0 | 1 | 2.71 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 23 | 0 | 1 | 4 | 3.04 | .292 | 1.20 | 5.5 | 5.5 | 5.9 | 26.2 | 16 | 9 | 9 | 4 | 16 | 17 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.65 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 16 | 0 | 0 | 0 | 3.38 | .287 | 1.17 | 7.1 | 3.4 | 8.3 | 24.0 | 19 | 11 | 9 | 3 | 9 | 22 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.04 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 57 | 4 | 1 | 1 | 0 | 7.50 | .429 | 2.17 | 11.3 | 8.3 | 7.5 | 12.0 | 15 | 12 | 10 | 3 | 11 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.58 |