| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 33 | 33 | 15 | 14 | 4.74 | .308 | 1.31 | 8.9 | 2.9 | 5.4 | 218.1 | 215 | 121 | 115 | 31 | 70 | 131 | 4 | 0 | 0 | 1 | 17 | 7 | 4 | 4.71 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 32 | 32 | 11 | 15 | 5.10 | .316 | 1.37 | 9.3 | 3.0 | 5.1 | 224.1 | 232 | 136 | 127 | 24 | 75 | 128 | 6 | 0 | 0 | 0 | 13 | 4 | 3 | 4.31 |
| SP | Lundgren, C.Lundgren, Carl $$ >> | 27 | 1907 | R | 43 | 31 | 31 | 12 | 11 | 3.86 | .312 | 1.34 | 7.4 | 4.8 | 3.5 | 214.1 | 175 | 100 | 92 | 24 | 113 | 84 | 3 | 0 | 0 | 2 | 18 | 4 | 1 | 5.31 |
| SP | Fernandez, S.Fernandez, Sid † $$ >> | 23 | 1985 | L | 49 | 30 | 30 | 19 | 8 | 3.72 | .329 | 1.44 | 7.8 | 5.2 | 7.7 | 188.2 | 163 | 89 | 78 | 20 | 108 | 161 | 2 | 0 | 0 | 0 | 16 | 7 | 3 | 4.51 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 59 | 0 | 4 | 6 | 2.58 | .260 | 1.04 | 5.5 | 4.0 | 10.6 | 66.1 | 40 | 21 | 19 | 11 | 29 | 78 | 0 | 37 | 3 | 0 | 0 | 1 | 0 | 4.17 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 73 | 0 | 1 | 2 | 3.13 | .237 | 0.91 | 6.6 | 1.7 | 8.8 | 97.2 | 71 | 36 | 34 | 12 | 18 | 95 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.27 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 55 | 0 | 2 | 1 | 4.55 | .292 | 1.22 | 7.6 | 3.5 | 6.0 | 57.1 | 48 | 30 | 29 | 5 | 22 | 38 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.02 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 34 | 0 | 1 | 2 | 6.03 | .338 | 1.50 | 10.2 | 3.5 | 7.3 | 31.1 | 35 | 22 | 21 | 7 | 12 | 25 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.58 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 29 | 0 | 1 | 0 | 5.08 | .344 | 1.57 | 10.4 | 4.1 | 7.9 | 33.2 | 38 | 22 | 19 | 9 | 15 | 29 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 6.15 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 3 | 0 | 0 | 0 | 3.38 | .385 | 1.88 | 18.0 | 4.5 | 18.0 | 2.2 | 4 | 1 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.50 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 20 | 0 | 5 | 3 | 3.22 | .302 | 1.27 | 8.7 | 2.8 | 3.0 | 81.0 | 78 | 32 | 29 | 11 | 25 | 27 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.10 |