| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 27 | 10 | 13 | 5.00 | .320 | 1.39 | 8.5 | 4.0 | 8.3 | 171.0 | 161 | 99 | 95 | 21 | 76 | 157 | 2 | 0 | 0 | 0 | 12 | 4 | 5 | 4.16 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 28 | 28 | 13 | 9 | 4.68 | .326 | 1.43 | 9.9 | 3.0 | 3.7 | 178.2 | 196 | 98 | 93 | 19 | 59 | 74 | 4 | 0 | 0 | 1 | 14 | 4 | 3 | 4.62 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 78 | 0 | 7 | 2 | 3.39 | .278 | 1.13 | 6.6 | 3.6 | 8.0 | 111.2 | 81 | 45 | 42 | 10 | 45 | 99 | 0 | 7 | 1 | 0 | 0 | 3 | 4 | 3.68 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 62 | 0 | 3 | 4 | 2.54 | .310 | 1.33 | 5.8 | 6.2 | 7.4 | 78.0 | 50 | 28 | 22 | 7 | 54 | 64 | 0 | 5 | 4 | 0 | 0 | 1 | 1 | 4.64 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 46 | 0 | 6 | 2 | 3.25 | .280 | 1.13 | 9.3 | 0.9 | 7.2 | 61.0 | 63 | 22 | 22 | 4 | 6 | 49 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 2.64 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 45 | 0 | 2 | 3 | 3.83 | .278 | 1.14 | 7.3 | 2.9 | 3.7 | 49.1 | 40 | 22 | 21 | 5 | 16 | 20 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 4.55 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 3 | 2 | 1 | 1 | 3.60 | .224 | 0.80 | 5.4 | 1.8 | 3.0 | 15.0 | 9 | 6 | 6 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 3.13 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 27 | 0 | 5 | 4 | 3.83 | .338 | 1.51 | 9.6 | 4.0 | 5.0 | 47.0 | 50 | 22 | 20 | 4 | 21 | 26 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 4.40 |