| SP | Koufax, S.Koufax, Sandy $ >> | 30 | 1965 | L | 97 | 24 | 24 | 10 | 10 | 3.85 | .293 | 1.22 | 8.5 | 2.5 | 6.7 | 177.2 | 167 | 80 | 76 | 19 | 50 | 131 | 7 | 0 | 0 | 1 | 13 | 4 | 3 | 3.83 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 24 | 24 | 14 | 6 | 2.27 | .253 | 1.00 | 6.5 | 2.5 | 4.7 | 198.1 | 143 | 56 | 50 | 9 | 55 | 104 | 8 | 0 | 0 | 3 | 19 | 3 | 8 | 3.42 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 23 | 23 | 15 | 4 | 1.99 | .237 | 0.93 | 5.4 | 3.0 | 7.3 | 167.2 | 100 | 37 | 37 | 8 | 56 | 135 | 3 | 0 | 0 | 2 | 20 | 0 | 1 | 3.01 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 23 | 23 | 10 | 7 | 3.82 | .304 | 1.29 | 7.5 | 4.1 | 7.1 | 150.2 | 125 | 70 | 64 | 21 | 69 | 118 | 0 | 0 | 0 | 0 | 11 | 3 | 6 | 4.69 |
| SP | Fernandez, S.Fernandez, Sid $$ >> | 23 | 1985 | L | 49 | 23 | 23 | 11 | 8 | 2.86 | .270 | 1.06 | 5.6 | 4.0 | 7.5 | 160.2 | 100 | 56 | 51 | 9 | 71 | 134 | 3 | 0 | 0 | 0 | 16 | 7 | 1 | 3.52 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 62 | 0 | 3 | 3 | 2.47 | .276 | 1.13 | 5.8 | 4.4 | 8.6 | 62.0 | 40 | 18 | 17 | 6 | 30 | 59 | 0 | 8 | 0 | 0 | 0 | 1 | 0 | 3.85 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 36 | 0 | 1 | 3 | 3.74 | .299 | 1.28 | 8.7 | 3.0 | 6.3 | 33.2 | 32 | 14 | 14 | 5 | 11 | 23 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 4.58 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 24 | 0 | 1 | 3 | 4.58 | .330 | 1.42 | 8.5 | 4.7 | 9.5 | 19.2 | 18 | 10 | 10 | 3 | 10 | 20 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.68 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 18 | 0 | 3 | 0 | 1.72 | .299 | 1.21 | 6.0 | 5.4 | 7.2 | 15.2 | 10 | 3 | 3 | 2 | 9 | 12 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.13 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 7 | 0 | 1 | 0 | 2.60 | .308 | 1.27 | 8.7 | 3.0 | 6.0 | 27.2 | 26 | 9 | 8 | 2 | 9 | 18 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.85 |