| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 29 | 29 | 12 | 7 | 4.47 | .299 | 1.26 | 8.7 | 2.6 | 5.4 | 177.1 | 171 | 89 | 88 | 23 | 52 | 106 | 4 | 0 | 0 | 0 | 14 | 4 | 4 | 4.44 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 28 | 28 | 10 | 14 | 4.52 | .304 | 1.30 | 7.7 | 4.0 | 5.5 | 165.1 | 142 | 86 | 83 | 22 | 73 | 100 | 2 | 0 | 0 | 1 | 19 | 2 | 4 | 4.88 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 28 | 28 | 13 | 7 | 3.72 | .307 | 1.31 | 8.1 | 3.8 | 4.6 | 193.2 | 173 | 88 | 80 | 14 | 81 | 98 | 5 | 0 | 0 | 1 | 17 | 3 | 2 | 4.23 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 27 | 27 | 9 | 11 | 4.03 | .318 | 1.37 | 7.4 | 5.0 | 3.9 | 167.1 | 137 | 81 | 75 | 17 | 92 | 73 | 1 | 0 | 0 | 1 | 15 | 5 | 1 | 5.19 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 73 | 0 | 6 | 4 | 3.42 | .314 | 1.30 | 7.9 | 3.9 | 9.2 | 94.2 | 82 | 38 | 36 | 6 | 41 | 96 | 0 | 6 | 1 | 0 | 0 | 7 | 7 | 3.32 |
| RP | Davis, W.Davis, Wade † >> | 29 | 2015 | R | 89 | 64 | 0 | 6 | 4 | 3.35 | .307 | 1.33 | 6.7 | 5.3 | 8.0 | 75.1 | 56 | 30 | 28 | 4 | 44 | 67 | 0 | 7 | 1 | 0 | 0 | 0 | 4 | 3.67 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 83 | 49 | 0 | 4 | 3 | 2.93 | .290 | 1.21 | 6.3 | 4.6 | 5.6 | 61.1 | 43 | 22 | 20 | 3 | 31 | 38 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 3.97 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 44 | 0 | 3 | 0 | 4.14 | .315 | 1.36 | 8.7 | 3.7 | 7.7 | 54.1 | 52 | 25 | 25 | 10 | 22 | 46 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 4.98 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 38 | 0 | 2 | 0 | 3.13 | .270 | 1.11 | 6.3 | 3.7 | 7.6 | 46.0 | 32 | 16 | 16 | 4 | 19 | 39 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.67 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 28 | 1 | 6 | 3 | 4.26 | .339 | 1.53 | 8.7 | 5.0 | 4.9 | 93.0 | 90 | 45 | 44 | 10 | 52 | 51 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.01 |