| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 4 | 4 | 1 | 1 | 5.74 | .304 | 1.28 | 8.7 | 3.1 | 5.2 | 26.2 | 25 | 18 | 17 | 4 | 9 | 15 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 5.00 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 5 | 5 | 4 | 0 | 2.77 | .273 | 1.13 | 6.2 | 3.9 | 7.2 | 39.0 | 27 | 12 | 12 | 1 | 17 | 31 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.05 |
| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 4 | 4 | 1 | 2 | 3.26 | .283 | 1.15 | 7.2 | 3.3 | 9.0 | 30.1 | 24 | 12 | 11 | 3 | 11 | 30 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 3.50 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 9 | 0 | 0 | 0 | 2.08 | .316 | 1.38 | 10.1 | 3.4 | 4.5 | 8.2 | 9 | 2 | 2 | 1 | 3 | 4 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 7 | 0 | 1 | 1 | 1.80 | .250 | 1.00 | 5.4 | 3.6 | 7.2 | 5.0 | 3 | 1 | 1 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 2 | 1 | 1 | 1 | 6.48 | .390 | 1.92 | 11.3 | 6.8 | 5.6 | 8.1 | 10 | 6 | 6 | 1 | 6 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.63 |