| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 24 | 24 | 7 | 12 | 4.66 | .301 | 1.28 | 8.8 | 2.7 | 9.7 | 156.1 | 153 | 86 | 81 | 27 | 47 | 168 | 1 | 0 | 0 | 0 | 12 | 2 | 1 | 4.04 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 23 | 23 | 8 | 7 | 4.88 | .313 | 1.30 | 8.6 | 3.1 | 9.1 | 147.2 | 141 | 80 | 80 | 23 | 51 | 149 | 0 | 0 | 0 | 0 | 12 | 10 | 1 | 4.25 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 85 | 22 | 22 | 3 | 8 | 6.85 | .358 | 1.64 | 10.9 | 4.0 | 9.9 | 111.2 | 134 | 89 | 85 | 17 | 49 | 122 | 0 | 0 | 0 | 0 | 7 | 4 | 6 | 4.23 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 79 | 22 | 21 | 8 | 7 | 5.19 | .328 | 1.45 | 8.9 | 4.1 | 6.6 | 137.0 | 135 | 85 | 79 | 30 | 63 | 100 | 6 | 0 | 0 | 1 | 9 | 3 | 3 | 5.83 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 22 | 22 | 10 | 10 | 4.97 | .319 | 1.39 | 9.4 | 3.1 | 6.5 | 146.2 | 153 | 82 | 81 | 23 | 51 | 105 | 6 | 0 | 0 | 2 | 7 | 2 | 3 | 4.70 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 47 | 0 | 2 | 5 | 3.72 | .253 | 0.98 | 6.5 | 2.3 | 13.2 | 58.0 | 42 | 24 | 24 | 5 | 15 | 85 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 2.07 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 44 | 0 | 2 | 2 | 4.13 | .318 | 1.38 | 9.9 | 2.4 | 9.4 | 48.0 | 53 | 22 | 22 | 9 | 13 | 50 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.23 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 33 | 0 | 3 | 3 | 5.97 | .343 | 1.57 | 9.7 | 4.6 | 11.7 | 37.2 | 40 | 25 | 25 | 9 | 19 | 48 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.11 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 25 | 0 | 2 | 1 | 2.97 | .300 | 1.25 | 8.7 | 2.7 | 12.0 | 30.1 | 29 | 10 | 10 | 5 | 9 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.50 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 67 | 4 | 1 | 0 | 3 | 6.52 | .408 | 2.07 | 13.0 | 7.0 | 10.0 | 9.2 | 13 | 7 | 7 | 1 | 7 | 10 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 4.56 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 45 | 0 | 3 | 5 | 3.74 | .286 | 1.18 | 7.0 | 3.8 | 13.2 | 45.2 | 35 | 19 | 19 | 6 | 19 | 66 | 0 | 18 | 1 | 0 | 0 | 1 | 1 | 3.13 |