| SP | Kershaw, C.Kershaw, Clayton $ >> | 28 | 2016 | L | 98 | 34 | 34 | 12 | 11 | 4.79 | .302 | 1.29 | 9.3 | 2.3 | 9.3 | 203.0 | 210 | 119 | 108 | 35 | 51 | 210 | 1 | 0 | 0 | 1 | 16 | 3 | 3 | 3.97 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 33 | 33 | 8 | 16 | 5.58 | .326 | 1.43 | 9.5 | 3.4 | 9.0 | 196.2 | 207 | 133 | 122 | 31 | 74 | 197 | 2 | 0 | 0 | 0 | 10 | 5 | 2 | 4.26 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 32 | 32 | 10 | 12 | 5.59 | .330 | 1.46 | 9.0 | 4.1 | 10.4 | 178.2 | 178 | 118 | 111 | 37 | 82 | 206 | 0 | 0 | 0 | 0 | 18 | 4 | 3 | 4.84 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 84 | 32 | 32 | 10 | 17 | 4.43 | .333 | 1.47 | 8.2 | 5.0 | 10.3 | 178.2 | 163 | 103 | 88 | 29 | 99 | 204 | 0 | 0 | 0 | 0 | 12 | 5 | 1 | 4.58 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 60 | 0 | 2 | 0 | 4.54 | .327 | 1.44 | 8.9 | 4.2 | 10.6 | 71.1 | 70 | 40 | 36 | 11 | 33 | 84 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.08 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 46 | 0 | 3 | 4 | 3.58 | .307 | 1.31 | 8.1 | 3.8 | 8.5 | 50.1 | 45 | 23 | 20 | 8 | 21 | 47 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.52 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 69 | 35 | 0 | 0 | 2 | 1.08 | .228 | 0.89 | 5.0 | 3.1 | 8.3 | 41.2 | 23 | 5 | 5 | 2 | 14 | 38 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 55 | 0 | 2 | 3 | 4.89 | .288 | 1.21 | 6.9 | 3.9 | 10.1 | 57.0 | 44 | 32 | 31 | 11 | 25 | 64 | 0 | 2 | 7 | 0 | 0 | 0 | 0 | 4.58 |