| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 6 | 6 | 2 | 2 | 3.77 | .267 | 1.09 | 7.5 | 2.3 | 9.4 | 43.0 | 36 | 18 | 18 | 5 | 11 | 45 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 3.19 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 6 | 6 | 2 | 4 | 6.09 | .346 | 1.59 | 9.0 | 5.3 | 11.9 | 34.0 | 34 | 24 | 23 | 9 | 20 | 45 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 5.56 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 6 | 6 | 1 | 3 | 7.18 | .338 | 1.53 | 11.9 | 2.0 | 9.0 | 31.1 | 41 | 27 | 25 | 8 | 7 | 31 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 5.03 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 5 | 5 | 1 | 2 | 7.12 | .355 | 1.62 | 9.9 | 4.8 | 7.5 | 30.1 | 33 | 24 | 24 | 9 | 16 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 6.93 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 5 | 5 | 2 | 2 | 4.18 | .307 | 1.33 | 9.0 | 3.1 | 6.5 | 32.1 | 32 | 15 | 15 | 3 | 11 | 23 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 3.81 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 15 | 0 | 2 | 1 | 4.58 | .321 | 1.36 | 6.9 | 5.8 | 9.5 | 17.2 | 13 | 9 | 9 | 3 | 11 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.29 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 9 | 0 | 0 | 0 | 6.55 | .340 | 1.55 | 11.5 | 2.5 | 7.4 | 11.0 | 14 | 8 | 8 | 2 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.55 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 6 | 0 | 0 | 1 | 3.38 | .294 | 1.13 | 6.8 | 3.4 | 11.3 | 8.0 | 6 | 3 | 3 | 0 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.00 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 9 | 0 | 0 | 0 | 0.87 | .162 | 0.58 | 3.6 | 1.8 | 9.9 | 10.1 | 4 | 1 | 1 | 0 | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.40 |