| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 63 | 23 | 23 | 8 | 9 | 5.32 | .331 | 1.46 | 9.9 | 3.2 | 7.8 | 133.2 | 147 | 86 | 79 | 29 | 48 | 115 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 5.26 |
| RP | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 94 | 66 | 0 | 8 | 2 | 3.00 | .267 | 1.06 | 6.1 | 3.4 | 10.6 | 84.0 | 57 | 30 | 28 | 9 | 32 | 99 | 0 | 8 | 3 | 0 | 0 | 3 | 1 | 3.29 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 61 | 0 | 2 | 5 | 3.30 | .288 | 1.21 | 6.0 | 4.9 | 8.5 | 71.0 | 47 | 29 | 26 | 13 | 39 | 67 | 0 | 5 | 1 | 0 | 0 | 0 | 3 | 5.14 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 56 | 49 | 0 | 5 | 4 | 4.96 | .323 | 1.43 | 7.9 | 5.0 | 8.6 | 49.0 | 43 | 28 | 27 | 5 | 27 | 47 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 4.06 |
| RP | Frohwirth, T.Frohwirth, Todd >> | 29 | 1991 | R | 37 | 32 | 0 | 0 | 0 | 4.17 | .304 | 1.28 | 9.0 | 2.8 | 6.3 | 36.2 | 36 | 17 | 17 | 4 | 11 | 25 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.06 |
| SP | Messersmith, A.Messersmith, Andy >> | 30 | 1975 | R | 42 | 14 | 1 | 2 | 1 | 5.89 | .371 | 1.72 | 10.5 | 5.3 | 4.5 | 36.2 | 42 | 25 | 24 | 6 | 21 | 18 | 0 | 1 | 1 | 0 | 1 | 2 | 0 | 6.08 |